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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC VR-144 / Wilmington;
DOI=10.1128/JB.186.17.5842-5855.2004; PubMed=15317790 [NCBI, ExPASy, EBI, Israel, Japan]
McLeod M.P.,
Qin X.,
Karpathy S.E.,
Gioia J.,
Highlander S.K.,
Fox G.E.,
McNeill T.Z.,
Jiang H.,
Muzny D.,
Jacob L.S.,
Hawes A.C.,
Sodergren E.,
Gill R.,
Hume J.,
Morgan M.,
Fan G.,
Amin A.G.,
Gibbs R.A.,
Hong C., ![]()
Yu X.-J.,
Walker D.H.,
Weinstock G.M.;
"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae.";
J. Bacteriol. 186:5842-5855(2004).
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- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Heterodimer of an alpha and a beta chain.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 326 AA [This is the length of the unprocessed precursor] |
Molecular weight: 36905 Da [This is the MW of the unprocessed precursor] |
CRC64: C10B2065264A3A3C [This is a checksum on the sequence] |
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10 20 30 40 50 60
MNIKPKKYKP IKEEYIKSFK DMLLLRRFEE KCGQLYGMGE IGGFCHLYIG QEAVISAVEL
70 80 90 100 110 120
IKKKGDSTIT SYRDHAHIIL AGTEPKYVLA ELMGRATGCS KGKGGSMHLF DIPNKFYGGH
130 140 150 160 170 180
GIVGAQVPIG TGLAFAEKYN GTNNICFTFL GDGAVNQGQV YEAFNMASLW GLPVVYIIEN
190 200 210 220 230 240
NEYSMGTSVS RSTFMRDLYK KGESFGIRGF QLDGMDFEEM YNGTKQVAEY VRENSFPVIL
250 260 270 280 290 300
EVKTYRYRGH SMSDPAKYRS KEEVAKYKER DTLVRIRQII LDNKYATEED LKAIERSVQE
310 320
VIKVAVEFSE NSPLPSEDEL YTDIYV
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Q68XA9 in FASTA format |
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