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UniProtKB/Swiss-Prot entry Q68XA0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UCRI_RICTY
Primary accession number Q68XA0
Secondary accession numbers None
Integrated into Swiss-Prot on May 15, 2007
Sequence was last modified on October 11, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 27)
Name and origin of the protein
Protein name Ubiquinol-cytochrome c reductase iron-sulfur subunit
Synonyms EC 1.10.2.2
Rieske iron-sulfur protein
RISP
Gene name
Name: petA
OrderedLocusNames: RT0261
From
Rickettsia typhi [TaxID: 785] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC VR-144 / Wilmington;
DOI=10.1128/JB.186.17.5842-5855.2004; PubMed=15317790 [NCBI, ExPASy, EBI, Israel, Japan]
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C., Yu X.-J., Walker D.H., Weinstock G.M.;
"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae.";
J. Bacteriol. 186:5842-5855(2004).
Comments
  • FUNCTION: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  • CATALYTIC ACTIVITY: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H+.
  • COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
  • SUBUNIT: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.
  • SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (Potential).
  • MISCELLANEOUS: The Rieske protein is a high potential 2Fe-2S protein.
  • SIMILARITY: Contains 1 Rieske domain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017197; AAU03742.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_067224.1; -.
3D structure databases
ModBase Q68XA0.
Enzyme and pathway databases
BioCyc RTYP257363:RT0261-MON; -.
Family and domain databases
InterPro IPR014349; Rieske.
IPR005805; Rieske_C.
IPR006317; Rieske_proteo.
IPR005806; Rieske_reg.
IPR006311; Tat.
Graphical view of domain structure.
Gene3D G3DSA:2.102.10.10; Rieske_reg; 1.
PANTHER PTHR10134; Rieske; 1.
Pfam PF00355; Rieske; 1.
Pfam graphical view of domain structure.
PRINTS PR00162; RIESKE.
TIGRFAMs TIGR01416; Rieske_proteo; 1.
TIGR01409; TAT_signal_seq; 1.
PROSITE PS51296; RIESKE; 1.
PS51318; TAT; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q68XA0.
Genome annotation databases
GeneID 2959250; -.
GenomeReviews AE017197_GR; RT0261.
KEGG rty:RT0261; -.
Phylogenomic databases
HOGENOM Q68XA0; -.
Genome annotation databases
CMR Q68XA0; RT0261.
Other
ProtoNet Q68XA0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; Cell membrane; Complete proteome; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Oxidoreductase; Transmembrane; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   177  177     Ubiquinol-cytochrome c reductase iron-sulfur subunit. PRO_0000286644
TRANSMEM   18    38  21     Potential. 
DOMAIN   88   175  88     Rieske. 
METAL   120   120        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   122   122        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
METAL   139   139        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   142   142        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
DISULFID   125   141        By similarity. 
Sequence information
Length: 177 AA [This is the length of the unprocessed precursor] Molecular weight: 19191 Da [This is the MW of the unprocessed precursor] CRC64: 3ADC9B2B6E69DB59 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSDTEDNRNK QTTRRDFIVL TASSVAAVGA ACAFWPIIDS LNPSTDVLAL SSIEVDLSSI 

        70         80         90        100        110        120 
AIGQTVTVKW QGKPIFITNR TPDGIASARA VKMSELIDPE KDEVRVKAGH DNWLVTIGIC 

       130        140        150        160        170 
THLGCVPLSN QGEYNGWFCP CHGSQYDSSG RVRKGPASLN LVVPPYIFIS DTKIRIG 

Q68XA0 in FASTA format

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