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UniProtKB/Swiss-Prot entry Q65GI7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_BACLD
Primary accession number Q65GI7
Secondary accession number Q62RZ5
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on October 25, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 33)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: BLi02959, BL00610
From
Bacillus licheniformis (strain DSM 13 / ATCC 14580) [TaxID: 279010] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1159/000079829; PubMed=15383718 [NCBI, ExPASy, EBI, Israel, Japan]
Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P., Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.;
"The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential.";
J. Mol. Microbiol. Biotechnol. 7:204-211(2004).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1186/gb-2004-5-10-r77; PubMed=15461803 [NCBI, ExPASy, EBI, Israel, Japan]
Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J., Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B., Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A., Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
"Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species.";
Genome Biol. 5:RESEARCH077.1-RESEARCH077.12(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017333; AAU41827.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CP000002; AAU24465.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_080103.1; -.
YP_092520.1; -.
3D structure databases
ModBase Q65GI7.
Enzyme and pathway databases
BioCyc BLIC279010:BL00610-MON; -.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q65GI7.
Genome annotation databases
GeneID 3028371; -.
3098442; -.
GenomeReviews CP000002_GR; BL00610.
AE017333_GR; BLi02959.
KEGG bld:BLi02959; -.
bli:BL00610; -.
NMPDR fig|279010.5.peg.3309; -.
Phylogenomic databases
HOGENOM Q65GI7; -.
Genome annotation databases
CMR Q65GI7; BLi02959.
Other
ProtoNet Q65GI7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   342  342     Ketol-acid reductoisomerase. PRO_0000226158
ACT_SITE   107   107        Potential. 
Sequence information
Length: 342 AA [This is the length of the unprocessed precursor] Molecular weight: 37469 Da [This is the MW of the unprocessed precursor] CRC64: 2FA57CDEB5709B10 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVKVYYNGDI KENVLAGKKV AVIGYGSQGH AHALNLKESG VDVIVGVRKG KSFAKAEEDG 

        70         80         90        100        110        120 
HQVFTVREAA EQADIVMVLL PDEQQQKVYE AEIKDGLQAG NSLVFAHGFN VHFHQIVPPA 

       130        140        150        160        170        180 
DVDVFLVAPK GPGHLVRRTF EQGAGVPALF AIYQDVTGEA KDKALAYAKA IGGARAGVLE 

       190        200        210        220        230        240 
TTFKEETETD LFGEQAVLCG GLTSLVKAGF ETLTEAGYQP ELAYFECLHE LKLIVDLMYE 

       250        260        270        280        290        300 
EGLAGMRYSI SDTAQWGDFV SGPRVVDEKV KESMKEVLKD IQNGTFAKEW IVENQVNRPR 

       310        320        330        340 
FNAINASENE HQIEVVGRKL REMMPFVKQG KKKEAVVAGA KN 

Q65GI7 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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