[1]	NUCLEOTIDE SEQUENCE [MRNA]. TISSUE=Olfactory epithelium; DOI=10.1021/bi00107a003; PubMed=1931961 [NCBI, ExPASy, EBI, Israel, Japan] Dear T.N., Campbell K., Rabbitts T.H.; "Molecular cloning of putative odorant-binding and odorant-metabolizing proteins."; Biochemistry 30:10376-10382(1991).

Comments

CATALYTIC ACTIVITY: 2 glutathione + H₂O₂ = glutathione disulfide + 2 H₂O.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed in the Bowman glands.
SIMILARITY: Belongs to the glutathione peroxidase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

M76733; AAA42094.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

B40464; B40464.

NP_671694.1; -.

3D structure databases

HSSP

P00435; 1GP1. [HSSP ENTRY / PDB]

ModBase

Q64625.

Protein family/group databases

PeroxiBase

3736; RnoGPx06.

Organism-specific databases

RGD

628789; Gpx6.

Family and domain databases

InterPro

IPR000889; Glut_peroxidase.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.30.10; Thioredoxin_fold; 1.

PANTHER

PTHR11592; Glut_peroxidase; 1.

Pfam

PF00255; GSHPx; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000303; Glutathion_perox; 1.

PRINTS

PR01011; GLUTPROXDASE.

PROSITE

PS00460; GLUTATHIONE_PEROXID_1; 1.
PS00763; GLUTATHIONE_PEROXID_2; 1.
PS51355; GLUTATHIONE_PEROXID_3; 1.
PROSITE graphical view of domain structure (profiles).

BLOCKS

Q64625.

Genome annotation databases

GeneID

259233; -.

KEGG

rno:259233; -.

Phylogenomic databases

HOVERGEN

Q64625; -.

Other

ProtoNet

Q64625.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Oxidoreductase; Peroxidase; Secreted; Signal.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 19`	`19`	`Potential.`
`CHAIN`	`20 221`	`202`	`Glutathione peroxidase 6.`	`PRO_0000013083`
`ACT_SITE`	`73 73`		`By similarity.`

Sequence information

Length: 221 AA [This is the length of the unprocessed precursor]

Molecular weight: 24961 Da [This is the MW of the unprocessed precursor]

CRC64: 92749EAF6A3EF48C [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTQQFWGPCL FSLFMAVLAQ ETLDPQKSKV DCNKGVAGTV YEYGANTLDG GEYVQFQQYA 

        70         80         90        100        110        120 
GKHILFVNVA SFCGLTATYP ELNTLQEELR PFNVSVLGFP CNQFGKQEPG KNSEILLGLK 

       130        140        150        160        170        180 
YVRPGGGFVP NFQLFEKGDV NGDNEQKVFS FLKSSCPPTS ELLGSPEHLF WDPMKVHDIR 

       190        200        210        220 
WNFEKFLVGP DGAPVMRWFH QTPVRVVQSD IMEYLNQTRT Q

Q64625 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools