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UniProtKB/Swiss-Prot entry Q64057


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AL7A1_RAT
Primary accession number Q64057
Secondary accession numbers None
Integrated into Swiss-Prot on November 15, 2002
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 60)
Name and origin of the protein
Protein name Alpha-aminoadipic semialdehyde dehydrogenase [Fragment]
Synonyms Alpha-AASA dehydrogenase
EC 1.2.1.31
Delta1-piperideine-6-carboxylate dehydrogenease
P6c dehydrogenase
Aldehyde dehydrogenase family 7 member A1
Antiquitin-1
Gene name
Name: Aldh7a1
Synonyms: Ald7a1
From
Rattus norvegicus (Rat) [TaxID: 10116] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
TISSUE=Intestinal mucosa;
DOI=10.1006/geno.1994.1279; PubMed=8088832 [NCBI, ExPASy, EBI, Israel, Japan]
Lee P., Kuhl W., Gelbart T., Kamimura T., West C., Beutler E.;
"Homology between a human protein and a protein of the green garden pea.";
Genomics 21:371-378(1994).
[2]
PROTEIN SEQUENCE OF 25-38 AND 116-126, AND MASS SPECTROMETRY.
STRAIN=Sprague-Dawley;
TISSUE=Spinal cord;
Lubec G., Afjehi-Sadat L.;
Submitted (NOV-2006) to UniProtKB.
[3]
TISSUE SPECIFICITY.
DOI=10.1006/geno.1997.5026; PubMed=9417906 [NCBI, ExPASy, EBI, Israel, Japan]
Skvorak A.B., Robertson N.G., Yin Y., Weremowicz S., Her H., Bieber F.R., Beisel K.W., Lynch E.D., Beier D.R., Morton C.C.;
"An ancient conserved gene expressed in the human inner ear: identification, expression analysis, and chromosomal mapping of human and mouse antiquitin (ATQ1).";
Genomics 46:191-199(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
S75019; AAB31967.2; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B54676; B54676.
UniGene Rn.7330
3D structure databases
HSSP P51977; 1BXS. [HSSP ENTRY / PDB]
SMR Q64057; 1-216.
ModBase Q64057.
Organism-specific databases
RGD 1308614; Aldh7a1.
Gene expression databases
ArrayExpress Q64057; -.
GermOnline ENSRNOG00000014645; Rattus norvegicus.
Family and domain databases
InterPro IPR016163; Ald_DHase_C.
IPR016160; Ald_DHase_CS.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; PARTIAL.
PS00687; ALDEHYDE_DEHYDR_GLU; PARTIAL.
BLOCKS Q64057.
Genome annotation databases
Ensembl ENSRNOG00000014645; Rattus norvegicus. [Contig view]
Phylogenomic databases
HOVERGEN Q64057; -.
Other
ProtoNet Q64057.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Direct protein sequencing; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   <1   228  >228     Alpha-aminoadipic semialdehyde dehydrogenase. PRO_0000056492
ACT_SITE   19    19        By similarity. 
NON_TER   1     1         
Sequence information
Length: 228 AA [This is the length of the partial sequence of the unprocessed precursor] Molecular weight: 25158 Da [This is the MW of the partial sequence of the unprocessed precursor] CRC64: F5DA69254AF35C16 [This is a checksum on the sequence]
        10         20         30         40         50         60 
SLVLPSALFA AVGTAGQRCT TVRRLFLHES IHDEVVDRLK NDYSQIRVGN PWDPNILYGP 

        70         80         90        100        110        120 
LHTKQAVSMF VQAVEEAKKE GGTVVYGGKV MDHPGNYVEP TIVTGLVHDA PIVHKETFAP 

       130        140        150        160        170        180 
ILYVFKFKNE EEVFEWNNKV KQELSSSIFT KDLGRIFRWL GPKGSDCGIV NVNIPTSGAE 

       190        200        210        220 
IGGAFGGEKH TGSGRESGSD AWKQYMRRST CTINYSTALP LAQGIKFQ 

Q64057 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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