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UniProtKB/Swiss-Prot entry Q60Y65


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HPPD_CAEBR
Primary accession number Q60Y65
Secondary accession number A8XSJ1
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on November 23, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 27)
Name and origin of the protein
Protein name 4-hydroxyphenylpyruvate dioxygenase
Synonyms EC 1.13.11.27
4-hydroxyphenylpyruvic acid oxidase
HPPDase
4HPPD
HPD
Gene name
Name: hpd-1
ORFNames: CBG18361
From
Caenorhabditis briggsae [TaxID: 6238] 
Taxonomy Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AF16;
DOI=10.1371/journal.pbio.0000045; PubMed=14624247 [NCBI, ExPASy, EBI, Israel, Japan]
Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P., Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W., Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A., Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E., Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K., Durbin R.M., Waterston R.H.;
"The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics.";
PLoS Biol. 1:166-192(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CAAC02000548; CAP35833.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
SMR Q60Y65; 7-367.
ModBase Q60Y65.
Organism-specific databases
WormBase WBGene00037803; Cbr-hpd-1.
Family and domain databases
InterPro IPR005956; 4OHPhenylPyrv_dOase.
IPR004360; Glyas_bleo-R_dOase.
Graphical view of domain structure.
PANTHER PTHR11959; HPP_dOase; 1.
Pfam PF00903; Glyoxalase; 2.
Pfam graphical view of domain structure.
PIRSF PIRSF009283; HPP_dOase; 1.
TIGRFAMs TIGR01263; 4HPPD; 1.
BLOCKS Q60Y65.
Other
ProtoNet Q60Y65.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   393  393     4-hydroxyphenylpyruvate dioxygenase. PRO_0000088394
METAL   182   182        Iron (By similarity). 
METAL   267   267        Iron (By similarity). 
METAL   350   350        Iron (By similarity). 
Sequence information
Length: 393 AA [This is the length of the unprocessed precursor] Molecular weight: 44600 Da [This is the MW of the unprocessed precursor] CRC64: 8A5C3CAF60DF0B42 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTTFDRGEKP DIGTLVAFDH VRFVVGNAKQ AAYWYCANFG FEPFAYKGLE TGSRITAQHA 

        70         80         90        100        110        120 
IKQDKIVFVF ESALLPDNTE LGEHLVQHGD GVKDVCFEVE DLDSIVAHAK AAGATIVRDI 

       130        140        150        160        170        180 
TEESDENGSV RFATLRTYGE TDHTLLERKK YKGAFLPGFK PHPMPPTFFH SLPRVGLNFL 

       190        200        210        220        230        240 
DHCVGNQPDL QMAPAVEWYE NILKFHRFWS VDDSMIHTEY SALRSIVVTN FEETIKMPIN 

       250        260        270        280        290        300 
EPASSNKKAV SQIQEFVDYY GGSGVQHIAL NTTDIITAIE ALRARGCEFL SIPSSYYDNL 

       310        320        330        340        350        360 
RQRLSVSSMK IKEDMDRLQK LHILVDFDEN GYLLQIFSKP CQDRPTLFLE IIQRQNHQGF 

       370        380        390 
GAGNFKALFE SIELEQTKRG NLFYENVKDG QHK 

Q60Y65 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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