ID   GPD1L_DANRE             Reviewed;         351 AA.
AC   Q5XIZ6;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   04-NOV-2008, entry version 40.
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase 1-like protein;
DE            EC=1.1.1.8;
GN   Name=gpd1l;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + NAD(+) = glycerone
CC       phosphate + NADH.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate
CC       dehydrogenase family.
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DR   EMBL; BC083522; AAH83522.1; -; mRNA.
DR   RefSeq; NP_001005934.1; -.
DR   UniGene; Dr.80185; -.
DR   SMR; Q5XIZ6; 3-346.
DR   Ensembl; ENSDARG00000040024; Danio rerio.
DR   GeneID; 449663; -.
DR   KEGG; dre:449663; -.
DR   ZFIN; ZDB-GENE-041010-220; gpd1l.
DR   HOGENOM; Q5XIZ6; -.
DR   HOVERGEN; Q5XIZ6; -.
DR   ArrayExpress; Q5XIZ6; -.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR013328; DHase_multihelical.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   InterPro; IPR017751; NAD-dep_Gly3P_DH_euk.
DR   InterPro; IPR006168; NAD-dep_Gly3P_DHase.
DR   InterPro; IPR011128; NAD-dep_Gly3P_DHase_N.
DR   InterPro; IPR006109; NAD_Gly3P_DHase_C.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   PANTHER; PTHR11728; NAD_Gly3P_DH; 1.
DR   Pfam; PF07479; NAD_Gly3P_dh_C; 1.
DR   Pfam; PF01210; NAD_Gly3P_dh_N; 1.
DR   PIRSF; PIRSF000114; Glycerol-3-P_dh; 1.
DR   PRINTS; PR00077; GPDHDRGNASE.
DR   ProDom; PD001278; NAD_Gly3P_C; 1.
DR   PROSITE; PS00957; NAD_G3PDH; FALSE_NEG.
PE   2: Evidence at transcript level;
KW   Cytoplasm; NAD; Oxidoreductase.
FT   CHAIN         1    351       Glycerol-3-phosphate dehydrogenase 1-like
FT                                protein.
FT                                /FTId=PRO_0000286514.
FT   NP_BIND      11     16       NAD (By similarity).
FT   REGION      271    272       Substrate binding (By similarity).
FT   ACT_SITE    205    205       Proton acceptor (By similarity).
FT   BINDING      98     98       NAD (By similarity).
FT   BINDING     121    121       Substrate (By similarity).
FT   BINDING     154    154       NAD; via amide nitrogen (By similarity).
FT   BINDING     271    271       NAD (By similarity).
FT   BINDING     298    298       NAD; via amide nitrogen (By similarity).
FT   BINDING     300    300       NAD (By similarity).
SQ   SEQUENCE   351 AA;  38285 MW;  13392C6CE9204871 CRC64;
     MAAPLKVCIV GSGNWGSAIA RIIGSNAQKL QCFATTVKMW VYEEMVNGKK LSEIINTEHE
     NVKYLPGYKL PENVVAVPQL RDAADGADLL VFVVPHQFIR KLCDEMMGCV SERARGITLI
     KGIDEGPEGL KLISDIIREK MGIDVSVLMG ANIANEVAAE KFCESTIGSK VLENGLLFKD
     LLQTPNFRIT VVDDADTVEL CGALKNIVAV GAGFCDGLQC GDNTKAAVIR LGLMEMIAFA
     KLFSKDDSVS SATFLESCGV ADLITTCYGG RNRRVAEAFA KTGKSIEELE KEMLNGQKLQ
     GPLTSAEVYH ILKQKGLVEK FPLFTAVYQI CFEDKPVRDM ITCLQSHPEH L
//