[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y., Kawai S., Ito S., Horikoshi K.; "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-K16."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Reduction of activated sulfate into sulfite (By similarity).
CATALYTIC ACTIVITY: Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the PAPS reductase family. CysH subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP006627; BAD63150.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_174111.1; -.

3D structure databases

ModBase

Q5WKF5.

Enzyme and pathway databases

BioCyc

BCLA66692:ABC0611-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004604;	Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0019379;	Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00063; -; 1.
PBIL [Tree]

InterPro

IPR011798; APS_reductase.
IPR004511; CysH.
IPR002500; PAPS_reduct.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.

Pfam

PF01507; PAPS_reduct; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR02055; APS_reductase; 1.
TIGR00434; cysH; 1.

BLOCKS

Q5WKF5.

Genome annotation databases

GeneID

3204683; -.

GenomeReviews

AP006627_GR; ABC0611.

KEGG

bcl:ABC0611; -.

NMPDR

fig|66692.3.peg.610; -.

Phylogenomic databases

HOGENOM

Q5WKF5; -.

Genome annotation databases

CMR

Q5WKF5; ABC0611.

Other

ProtoNet

Q5WKF5.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 241`	`241`		`Phosphoadenosine phosphosulfate reductase.`	`PRO_1000075070`

Sequence information

Length: 241 AA [This is the length of the unprocessed precursor]

Molecular weight: 28151 Da [This is the MW of the unprocessed precursor]

CRC64: 672C682B65E037A3 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAYVFEQMEA TDYEKVNTKL KNRDSLDILR WANQTYGEKL VYACSFGAEA MVLLDLLSKI 

        70         80         90        100        110        120 
QKEAHILFLD TDFHFAETYE LIERVKERYP TFRINMAKPA LSPEEQAERY GDELWLKNPD 

       130        140        150        160        170        180 
QCCQIRKLDV LARELEPYDA WLSGLRREQS PTRANTEFVN QDKRFKKVKV CPLIHWTEEE 

       190        200        210        220        230        240 
IWMYIKLHQL PYNELHDQHY PSIGCTYCTK AVMPGEDARS GRWAGTGKTE CGLHAPTKGD 


S

Q5WKF5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools