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UniProtKB/Swiss-Prot entry Q5RAS0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ACADS_PONAB
Primary accession number Q5RAS0
Secondary accession numbers None
Integrated into Swiss-Prot on June 12, 2007
Sequence was last modified on December 21, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 26)
Name and origin of the protein
Protein name Short-chain specific acyl-CoA dehydrogenase, mitochondrial [Precursor]
Synonyms SCAD
EC 1.3.99.2
Butyryl-CoA dehydrogenase
Gene name
Name: ACADS
From
Pongo abelii (Sumatran orangutan) [TaxID: 9601] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Heart;
The German cDNA consortium;
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR858942; CAH91140.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
SMR Q5RAS0; 28-411.
ModBase Q5RAS0.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
QuickGo view.
Family and domain databases
InterPro IPR006091; Acyl-CoA_DHase/Oxase_M.
IPR006089; Acyl-CoA_DHase_CS.
IPR006092; Acyl-CoA_DHase_N.
IPR006090; Acyl-CoA_Oxase/DHase_1.
IPR013786; AcylCoA_DH/ox_N.
IPR013764; AcylCoA_oxidase/DH_1/2_C.
Graphical view of domain structure.
Gene3D G3DSA:2.40.110.10; Acyl_CoA_DH/ox_M; 1.
G3DSA:1.10.540.10; AcylCoA_DH/ox_N; 1.
G3DSA:1.20.140.10; AcylCoA_DH_1/2_C; 1.
Pfam PF00441; Acyl-CoA_dh_1; 1.
PF02770; Acyl-CoA_dh_M; 1.
PF02771; Acyl-CoA_dh_N; 1.
Pfam graphical view of domain structure.
PROSITE PS00072; ACYL_COA_DH_1; 1.
PS00073; ACYL_COA_DH_2; 1.
BLOCKS Q5RAS0.
Phylogenomic databases
HOVERGEN Q5RAS0; -.
Other
ProtoNet Q5RAS0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
FAD; Fatty acid metabolism; Flavoprotein; Lipid metabolism; Mitochondrion; Oxidoreductase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    24  24     Mitochondrion (By similarity). 
CHAIN   25   412  388     Short-chain specific acyl-CoA dehydrogenase, mitochondrial. PRO_0000290193
NP_BIND   152   161  10     FAD (By similarity). 
NP_BIND   185   187  3     FAD (By similarity). 
NP_BIND   365   369  5     FAD (By similarity). 
NP_BIND   394   396  3     FAD (By similarity). 
ACT_SITE   392   392        Proton acceptor (By similarity). 
BINDING   297   297        FAD (By similarity). 
Sequence information
Length: 412 AA [This is the length of the unprocessed precursor] Molecular weight: 44435 Da [This is the MW of the unprocessed precursor] CRC64: 7192364FDD45CF4C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAAALLARAS GPVRRALRPR AWRQLHTIYQ SVELPETHQM LLQTCRDFAE KELFPIAAQV 

        70         80         90        100        110        120 
DKEHLFPAAQ VKKMGGLGLL AMDVPEELGG AGLDYLAYAI AMEEISRGCA STGVIMSVNN 

       130        140        150        160        170        180 
SLYLGPILKF GSKEQKQKWV TPFTSGDKIG CFALSEPGNG SDAGAASTTA RAEGDSWVLN 

       190        200        210        220        230        240 
GTKAWITNAW EASAAVVFAS TDRALQNKGI SAFLVPMPTP GLTLGKKEDK LGIRGSSTAN 

       250        260        270        280        290        300 
LIFEDCRIPK DSILGEPGMG FKIAMQTLDM GRIGIASQAL GIAQTALDCA VNYAENRMAF 

       310        320        330        340        350        360 
GAPLTKLQVI QFKLADMALA LESARLLTWR AAMLKDNKKP FIKEAAMAKL AASEAATAIS 

       370        380        390        400        410 
HQAIQILGGM GYVTEMPAER HYRDARITEI YEGTSEIQRL VIAGHLLRSY RS
Q5RAS0 in FASTA format

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