ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q5NXP4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name ILVC_AZOSE
Primary accession number Q5NXP4
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on January 4, 2005 (Sequence version 1)
Annotations were last modified on    September 23, 2008 (Entry version 27)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: AZOSEA40450
ORFNames: ebA7134
From
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) [TaxID: 76114] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales; Rhodocyclaceae; Aromatoleum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1007/s00203-004-0742-9; PubMed=15551059 [NCBI, ExPASy, EBI, Israel, Japan]
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.;
"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1.";
Arch. Microbiol. 183:27-36(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR555306; CAI10170.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_161071.1; -.
3D structure databases
SMR Q5NXP4; 1-327.
ModBase Q5NXP4.
Enzyme and pathway databases
BioCyc ASP76114:EBA7134-MON; -.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q5NXP4.
Genome annotation databases
GeneID 3181730; -.
GenomeReviews CR555306_GR; AZOSEA40450.
KEGG eba:ebA7134; -.
NMPDR fig|76114.4.peg.4061; -.
Phylogenomic databases
HOGENOM Q5NXP4; -.
Genome annotation databases
CMR Q5NXP4; AZOSEA40450.
Other
ProtoNet Q5NXP4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   338  338     Ketol-acid reductoisomerase. PRO_0000226154
ACT_SITE   107   107        Potential. 
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 36966 Da [This is the MW of the unprocessed precursor] CRC64: EFAD5A86A348B1C5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKVYYDKDAD LSLIKGKQIT IVGYGSQGHA HAQNLKDSGC KVTVGLRKSG ASWKKAEAAG 

        70         80         90        100        110        120 
LDVREVAEAV SNADIVMILL PDENIPGVYY NDVEPNIKQG ATLAFAHGFN VHYNQVVPRD 

       130        140        150        160        170        180 
DLDVIMVAPK GPGHTVRSEY LKGGGVPSLI AVHQDRSGKA KDIALSYAAA NGGTKGGVIE 

       190        200        210        220        230        240 
TNFREETETD LFGEQAVLCG GAVELVKMGF ETLTEAGYAP EMAYFECLHE LKLIVDLMYE 

       250        260        270        280        290        300 
GGIANMNYSI SNNAEYGEYV TGPEVINEQS REAMRAALKR IQTGEYAKMF IQEGRTNYPS 

       310        320        330 
MTARRRLNAA HPIEQVGGQL RDMMPWIKKN KLVDQSKN
Q5NXP4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!