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UniProtKB/Swiss-Prot entry Q5KIK5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CCPR_CRYNE
Primary accession number Q5KIK5
Secondary accession number Q55TT2
Integrated into Swiss-Prot on December 20, 2005
Sequence was last modified on February 15, 2005 (Sequence version 1)
Annotations were last modified on    September 23, 2008 (Entry version 33)
Name and origin of the protein
Protein name Cytochrome c peroxidase, mitochondrial [Precursor]
Synonyms CCP
EC 1.11.1.5
Gene name
Name: CCP1
OrderedLocusNames: CND02630, CNBD3710
From
Cryptococcus neoformans (Filobasidiella neoformans) [TaxID: 5207] 
Taxonomy Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Tremellaceae; Filobasidiella; Filobasidiella/Cryptococcus neoformans species complex.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=B-3501A, and JEC21;
DOI=10.1126/science.1103773; PubMed=15653466 [NCBI, ExPASy, EBI, Israel, Japan]
Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
"The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans.";
Science 307:1321-1324(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017344; AAW42936.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAEY01000020; EAL21317.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_570243.1; -.
XP_775964.1; -.
UniGene Fne.3348
3D structure databases
ModBase Q5KIK5.
Protein family/group databases
PeroxiBase 2357; CnCcP01_JEC21.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
QuickGo view.
Family and domain databases
InterPro IPR002207; Asc_perxdse.
IPR002016; Haem_peroxidase_pln/fun/bac.
Graphical view of domain structure.
Pfam PF00141; peroxidase; 1.
Pfam graphical view of domain structure.
PRINTS PR00459; ASPEROXIDASE.
PR00458; PEROXIDASE.
PROSITE PS00435; PEROXIDASE_1; 1.
PS00436; PEROXIDASE_2; 1.
PS50873; PEROXIDASE_4; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q5KIK5.
Genome annotation databases
GeneID 3257130; -.
4935760; -.
GenomeReviews AE017344_GR; CND02630.
KEGG cnb:CNBD3710; -.
cne:CND02630; -.
Phylogenomic databases
HOGENOM Q5KIK5; -.
Other
ProtoNet Q5KIK5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Heme; Iron; Metal-binding; Mitochondrion; Oxidoreductase; Peroxidase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    17  17     Mitochondrion (Potential). 
CHAIN   18   377  360     Cytochrome c peroxidase, mitochondrial. PRO_0000045289
ACT_SITE   138   138        Proton acceptor (By similarity). 
ACT_SITE   277   277        Tryptophan radical intermediate (By similarity). 
METAL   261   261        Iron (heme axial ligand). 
SITE   134   134  1     Transition state stabilizer (By similarity). 
Sequence information
Length: 377 AA [This is the length of the unprocessed precursor] Molecular weight: 42112 Da [This is the MW of the unprocessed precursor] CRC64: 23FFFFF4EF188CB4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSFRAPNLIR SAAGRRASQT LNLRSQVIRR RFATEGGPEI TKPSSPRSSN TRYLLAGVGI 

        70         80         90        100        110        120 
AAVGAAYYFY GTGRTAHDSA NKADTVVRGA VATVEAKTGL RRGKDEYQKV YNRIAETLEK 

       130        140        150        160        170        180 
EGYDDGSLAP VLLRLAWHSS GTYNKEDGTG GSNFATMRFK PEAEHSANNG LHVAREHMEK 

       190        200        210        220        230        240 
IKQEFPWISY GDLWTLGGVC AVQESGGPTI PWRPGRIDGF EAQVTPDGRL PDASQAQDHL 

       250        260        270        280        290        300 
RFIFNRMGFN DQEIVALSGA HAMGRCHTNR SGFEGPWTFS PVTFSNQYFA LLRDEPWQWK 

       310        320        330        340        350        360 
KWTGPAQYED KNTKTLMMLP TDMALLKDKS FKKYVDIYAD NEEKFFSDFA KAFSKLIELG 

       370 
VPERQWAGEP WTLGTSD 

Q5KIK5 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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