Pyruvate synthase subunit porC
     (EC 1.2.7.1)
     (Pyruvate oxidoreductase gamma chain)
     (POR)
     (Pyruvic-ferredoxin oxidoreductase subunit gamma)
Ketoisovalerate oxidoreductase subunit vorC
     (VOR)
     (EC 1.2.7.7)
     (2-oxoisovalerate oxidoreductase gamma chain)
     (2-oxoisovalerate ferredoxin reductase subunit gamma)

Gene name

	Name:	porG
	OrderedLocusNames:	TK1978

From

Pyrococcus kodakaraensis (Thermococcus kodakaraensis)

[TaxID: 69014]

[HAMAP proteome]

Taxonomy

Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Thermococcus.

Protein existence

4: Predicted;

References

[1]

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KOD1;
DOI=10.1101/gr.3003105; PubMed=15710748 [NCBI, ExPASy, EBI, Israel, Japan]
Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
Genome Res. 15:352-363(2005).

Comments

CATALYTIC ACTIVITY: Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO₂ + 2 reduced ferredoxin + 2 H⁺.
CATALYTIC ACTIVITY: 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO₂ + 2 reduced ferredoxin + H⁺.
SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP006878; BAD86167.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_184391.1; -.

3D structure databases

ModBase

Q5JIK2.

Enzyme and pathway databases

BioCyc

TKOD69014:TK1978-MON; -.

Ontologies

GO:0043807;	Molecular function: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity (inferred from electronic annotation from EC).
GO:0019164;	Molecular function: pyruvate synthase activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

InterPro

IPR011894; PorC_KorC.
IPR002869; Pyrv_Fd/Flavodoxin_OxRdtase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.

Pfam

PF01558; POR; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR02175; PorC_KorC; 1.

BLOCKS

Q5JIK2.

Genome annotation databases

3235685; -.

AP006878_GR; TK1978.

tko:TK1978; -.

fig|69014.3.peg.1827; -.

Phylogenomic databases

HOGENOM

Q5JIK2; -.

Genome annotation databases

CMR

Q5JIK2; TK1978.

Other

ProtoNet

Q5JIK2.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 185`	`185`		`Pyruvate/ketoisovalerate oxidoreductases common subunit gamma.`	`PRO_0000099916`

Sequence information

Length: 185 AA [This is the length of the unprocessed precursor]

Molecular weight: 19693 Da [This is the MW of the unprocessed precursor]

CRC64: 4ACBC76A5E2DD707 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIEIRFHGRG GQGAVTAANI LASAAFKEGK YVQAFPFFGV ERRGAPVTAF TRIDDKPIRI 

        70         80         90        100        110        120 
KTQIYEPDVV VVLDPSLLDT VDVTAGLKDG GIVIVNTEKS KEEVLEKLKK KPGKLALVDA 

       130        140        150        160        170        180 
TGIALEILGL PITNTAILGA VAKATGLVKL ESVQEAIKET FSGALGEKNA KAAEEAFNKT 


VVYEL

Q5JIK2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools