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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.187.7.2426-2438.2005; PubMed=15774886 [NCBI, ExPASy, EBI, Israel, Japan]
Gill S.R.,
Fouts D.E.,
Archer G.L.,
Mongodin E.F.,
DeBoy R.T.,
Ravel J.,
Paulsen I.T.,
Kolonay J.F.,
Brinkac L.M.,
Beanan M.J.,
Dodson R.J.,
Daugherty S.C.,
Madupu R.,
Angiuoli S.V.,
Durkin A.S.,
Haft D.H.,
Vamathevan J.J.,
Khouri H.,
Utterback T.R., ![]()
Lee C.,
Dimitrov G.,
Jiang L.,
Qin H.,
Weidman J.,
Tran K.,
Kang K.H.,
Hance I.R.,
Nelson K.E.,
Fraser C.M.;
"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain.";
J. Bacteriol. 187:2426-2438(2005).
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- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Heterodimer of an alpha and a beta chain.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 370 AA [This is the length of the unprocessed precursor] |
Molecular weight: 41330 Da [This is the MW of the unprocessed precursor] |
CRC64: F691D1D8C2E3EEB4 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MAPKLQAQFD AVKVLNETQS KFEMVQILDE DGNVVNEDLV PDLTDEQLVE LMERMVWTRI
70 80 90 100 110 120
LDQRSISLNR QGRLGFYAPT AGQEASQLAS QYALESEDFI LPGYRDVPQI IWHGLPLTDA
130 140 150 160 170 180
FLFSRGHFKG NQFPEGVNAL SPQIIIGAQY IQTAGVAFGL KKRGKNAVAI TYTGDGGSSQ
190 200 210 220 230 240
GDFYEGINFA SAYKAPAIFV IQNNNYAIST PRSKQTAAET LAQKAISVGI PGIQVDGMDA
250 260 270 280 290 300
LAVYQATLEA RERAVAGEGP TVIETLTYRY GPHTMAGDDP TRYRTSDEDA EWEKKDPLVR
310 320 330 340 350 360
FRKYLEAKGL WNEDKENEVV ERAKSEIKAA IKEADNTEKQ TVTSLMDIMY EEMPQNLAEQ
370
YEIYKEKESK
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Q5HQ76 in FASTA format |
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