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UniProtKB/Swiss-Prot entry Q5HPC6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ODO1_STAEQ
Primary accession number Q5HPC6
Secondary accession numbers None
Integrated into Swiss-Prot on January 24, 2006
Sequence was last modified on February 15, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 26)
Name and origin of the protein
Protein name 2-oxoglutarate dehydrogenase E1 component
Synonyms EC 1.2.4.2
Alpha-ketoglutarate dehydrogenase
Gene name
Name: odhA
OrderedLocusNames: SERP0986
From
Staphylococcus epidermidis (strain ATCC 35984 / RP62A) [TaxID: 176279] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.187.7.2426-2438.2005; PubMed=15774886 [NCBI, ExPASy, EBI, Israel, Japan]
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.;
"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain.";
J. Bacteriol. 187:2426-2438(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000029; AAW54333.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_188564.1; -.
3D structure databases
ModBase Q5HPC6.
Enzyme and pathway databases
BioCyc SEPI176279:SERP0986-MON; -.
Ontologies
GO
GO:0004591; Molecular function: oxoglutarate dehydrogenase (succinyl-transferring) activity (inferred from electronic annotation from HAMAP).
GO:0030976; Molecular function: thiamin pyrophosphate binding (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01169; -; 1.
PBIL [Tree]
InterPro IPR011603; 2oxoglutarate_DHase_E1.
IPR001017; DHase_E1.
IPR005475; Transketo_Cen_R.
Graphical view of domain structure.
PANTHER PTHR23152; 2oxoglutarate_DH_E1; 1.
Pfam PF00676; E1_dh; 1.
PF02779; Transket_pyr; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000157; Oxoglu_dh_E1; 1.
TIGRFAMs TIGR00239; 2oxo_dh_E1; 1.
BLOCKS Q5HPC6.
Genome annotation databases
GeneID 3242079; -.
GenomeReviews CP000029_GR; SERP0986.
KEGG ser:SERP0986; -.
NMPDR fig|176279.3.peg.1064; -.
TIGR SERP0986; -.
Phylogenomic databases
HOGENOM Q5HPC6; -.
Other
ProtoNet Q5HPC6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Oxidoreductase; Thiamine pyrophosphate.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   934  934     2-oxoglutarate dehydrogenase E1 component. PRO_0000162182
Sequence information
Length: 934 AA [This is the length of the unprocessed precursor] Molecular weight: 105671 Da [This is the MW of the unprocessed precursor] CRC64: 711FD468A5FB2EC5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTKNKKEFTE APVNFGANLG LMLDLYDDYL QDPSSVPEDL QVLFSTIKTG EAHIEAKPTT 

        70         80         90        100        110        120 
DGGGSQAGDS TIKRVMRLID NIRQYGHLKA DIYPVNPPER QNVPKLEIED FDLDKETLEK 

       130        140        150        160        170        180 
ISSGIVSEHF KDIYDNAYDA IVRMERRYKG PIAFEYTHIN NNKERVWLKR RIETPYKASL 

       190        200        210        220        230        240 
NDNQKKELFK KLAHVEGFEK YLHKNFVGAK RFSIEGVDTL VPMLQHTITL AGNEGIKNIQ 

       250        260        270        280        290        300 
IGMAHRGRLN VLTHVLEKPY EMMISEFMHT DPMKFLPEDG SLELTSGWTS DVKYHLGGVK 

       310        320        330        340        350        360 
TTNSYGIEQR ISLANNPSHL EIVAPVVAGK TRAAQDNTHQ VGGPSTDFHK AMPIIIHGDA 

       370        380        390        400        410        420 
AYPGQGINFE TMNLGSLKGY STGGSLHIIT NNRIGFTTEP FDGRSTTYSS DVAKGYDVPI 

       430        440        450        460        470        480 
LHVNADDVEA TIEAIEIAME FRKEFHKDVV IDLVGYRRYG HNEMDEPSIT NPVPYQNIRK 

       490        500        510        520        530        540 
HDSVEILYGK KLVDEGIISE DEMNEVIDSV QKEMRTAHDK IDKNDKMNNP DMEKPESLQL 

       550        560        570        580        590        600 
PLQSDTKDFS FDHLKEINDA MLDYPKDFHV LKKLNKVLEK RREPFEKEGG LVDWAQAEQL 

       610        620        630        640        650        660 
AFATILQDGT SIRLTGQDSE RGTFSHRHAV LHDEENGNTF TPLHHVPQQQ ATFDIHNSPL 

       670        680        690        700        710        720 
SEAAVVGFEY GYNVENKGNF NIWEAQYGDF SNMSQMMFDN FLSSSRAKWG ERSGLTLFLP 

       730        740        750        760        770        780 
HAFEGQGPEH SSARLERFLQ LAAENNSTVV NLSSASNYFH LLRAQAASLD TLEMRPLIVM 

       790        800        810        820        830        840 
SPKSLLRNKT VAKPIDEFTS GGFKPIITED IDEQKVKKVI LASGKMYIDL KEYLAKNPND 

       850        860        870        880        890        900 
SILLIAVERL YPFPEEEIKE VLKSLPHLEN VSWVQEEPKN QGAWLFVYPY LKALVANKYD 

       910        920        930 
LTYHGRIQRA APAEGDGEIH KLVQTKIIES SINN
Q5HPC6 in FASTA format

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