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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.187.7.2426-2438.2005; PubMed=15774886 [NCBI, ExPASy, EBI, Israel, Japan]
Gill S.R.,
Fouts D.E.,
Archer G.L.,
Mongodin E.F.,
DeBoy R.T.,
Ravel J.,
Paulsen I.T.,
Kolonay J.F.,
Brinkac L.M.,
Beanan M.J.,
Dodson R.J.,
Daugherty S.C.,
Madupu R.,
Angiuoli S.V.,
Durkin A.S.,
Haft D.H.,
Vamathevan J.J.,
Khouri H.,
Utterback T.R., ![]()
Lee C.,
Dimitrov G.,
Jiang L.,
Qin H.,
Weidman J.,
Tran K.,
Kang K.H.,
Hance I.R.,
Nelson K.E.,
Fraser C.M.;
"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain.";
J. Bacteriol. 187:2426-2438(2005).
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- FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
- CATALYTIC ACTIVITY: Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
- COFACTOR: Thiamine pyrophosphate (By similarity).
- SUBUNIT: Heterodimer of an alpha and a beta chain.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 325 AA [This is the length of the unprocessed precursor] |
Molecular weight: 35216 Da [This is the MW of the unprocessed precursor] |
CRC64: EDFFFCB83E726E0F [This is a checksum on the sequence] |
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10 20 30 40 50 60
MAQMTMVQAI NDALKTELKN DQDVLIFGED VGVNGGVFRV TEGLQKEFGE DRVFDTPLAE
70 80 90 100 110 120
SGIGGLAMGL AVEGFRPVME VQFLGFVFEV FDAIAGQIAR TRFRSGGTKT APVTIRGPFG
130 140 150 160 170 180
GGVHTPELHA DNLEGILAQS PGLKVVIPSG PYDAKGLLIS SIRSNDPVVY LEHMKLYRSF
190 200 210 220 230 240
REEVPEEEYT IDIGKANVKK EGNDISIITY GAMVQESMKA AEELEKDGYS VEVIDLRTVQ
250 260 270 280 290 300
PIDVDTIVAS VEKTGRAVVV QEAQRQAGVG AAVVAELSER AILSLEAPIG RVAAADTIYP
310 320
FTQAENVWLP NKNDIIEKAK ETLEF
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Q5HGZ0 in FASTA format |
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