ID   MQO2_STAAC              Reviewed;         498 AA.
AC   Q5HCU5;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   04-NOV-2008, entry version 20.
DE   RecName: Full=Probable malate:quinone oxidoreductase 2;
DE            EC=1.1.99.16;
DE   AltName: Full=Malate dehydrogenase [acceptor] 2;
DE   AltName: Full=MQO 2;
GN   Name=mqo2; OrderedLocusNames=SACOL2623;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15774886; DOI=10.1128/JB.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T.,
RA   Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J.,
RA   Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S.,
RA   Haft D.H., Vamathevan J.J., Khouri H., Utterback T.R., Lee C.,
RA   Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H.,
RA   Hance I.R., Nelson K.E., Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete
RT   genome analysis of an early methicillin-resistant Staphylococcus
RT   aureus strain and a biofilm-producing methicillin-resistant
RT   Staphylococcus epidermidis strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- CATALYTIC ACTIVITY: (S)-malate + acceptor = oxaloacetate + reduced
CC       acceptor.
CC   -!- COFACTOR: FAD (By similarity).
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC   -!- SIMILARITY: Belongs to the MQO family.
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DR   EMBL; CP000046; AAW38622.1; -; Genomic_DNA.
DR   RefSeq; YP_187412.1; -.
DR   GeneID; 3237074; -.
DR   GenomeReviews; CP000046_GR; SACOL2623.
DR   KEGG; sac:SACOL2623; -.
DR   TIGR; SACOL2623; -.
DR   HOGENOM; Q5HCU5; -.
DR   BioCyc; SAUR93062:SACOL2623-MON; -.
DR   GO; GO:0008924; F:malate dehydrogenase (acceptor) activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:HAMAP.
DR   HAMAP; MF_00212; -; 1.
DR   InterPro; IPR006231; Malate_quinone_OxRdtase.
DR   Pfam; PF06039; Mqo; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   Complete proteome; FAD; Flavoprotein; Oxidoreductase;
KW   Tricarboxylic acid cycle.
FT   CHAIN         1    498       Probable malate:quinone oxidoreductase 2.
FT                                /FTId=PRO_0000128738.
SQ   SEQUENCE   498 AA;  55999 MW;  7D8D5ED706A4D183 CRC64;
     MAKSNSKDIV LIGAGVLSTT FGSMLKEIEP DWNIHVYERL DRPAIESSNE RNNAGTGHAA
     LCELNYTVLQ PDGSIDIEKA KVINEEFEIS KQFWGHLVKS GSIENPREFI NPLPHISYVR
     GKNNVKFLKD RYEAMKAFPM FDNIEYTEDI EVMKKWIPLM MKGREDNPGI MAASKIDEGT
     DVNFGELTRK MAKSIEAHPN ATVQFNHEVV DFEQLSNGQW EVTVKNRLTG EKFKQVTDYV
     FIGAGGGAIP LLQKTGIPES KHLGGFPISG QFLACTNPQV IEQHDAKVYG KEPPGTPPMT
     VPHLDTRYID GQRTLLFGPF ANVGPKFLKN GSNLDLFKSV KTYNITTLLA AAVKNLPLIK
     YSFDQVIMTK EGCMNHLRTF YPEARNEDWQ LYTAGKRVQV IKDTPEHGKG FIQFGTEVVN
     SQDHTVIALL GESPGASTSV SVALEVLERN FPEYKTEWAP KIKKMIPSYG ESLIEDEKLM
     RKIRKQTSKD LELGYYEN
//