ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q5FHY3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name GUAC_LACAC
Primary accession number Q5FHY3
Secondary accession numbers None
Integrated into Swiss-Prot on March 29, 2005
Sequence was last modified on March 1, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 24)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: LBA1893
From
Lactobacillus acidophilus [TaxID: 1579] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NCFM;
DOI=10.1073/pnas.0409188102; PubMed=15671160 [NCBI, ExPASy, EBI, Israel, Japan]
Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L., McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S., Hamrick A., Cano R., Klaenhammer T.R.;
"Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM.";
Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000033; AAV43691.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_194722.1; -.
3D structure databases
ModBase Q5FHY3.
Enzyme and pathway databases
BioCyc LACI272621:LBA1893-MON; -.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS Q5FHY3.
Genome annotation databases
GeneID 3251822; -.
GenomeReviews CP000033_GR; LBA1893.
KEGG lac:LBA1893; -.
NMPDR fig|272621.3.peg.1815; -.
Phylogenomic databases
HOGENOM Q5FHY3; -.
Genome annotation databases
CMR Q5FHY3; LBA1893.
Other
ProtoNet Q5FHY3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   330  330     GMP reductase. PRO_0000093758
NP_BIND   209   232  24     NADP (Potential). 
ACT_SITE   180   180        Thioimidate intermediate (By similarity). 
Sequence information
Length: 330 AA [This is the length of the unprocessed precursor] Molecular weight: 36657 Da [This is the MW of the unprocessed precursor] CRC64: 3E8A176D3B43A018 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSNYFSMEAF DYDDIQLIPN KGIIKSRRDA DTSVKFGNRT FKIPVVPANM ESVIDDKLAV 

        70         80         90        100        110        120 
WLAENDYYYV MHRFEPEKRI PFIKMMHEKG LFASISVGIK DSEYDFIDEL VKQNLKPEYI 

       130        140        150        160        170        180 
TIDVAHGHSV YVIKMIKYIK EKLPNSFLTA GNIATPEAVR ELENAGADAT KVGVGPGKAC 

       190        200        210        220        230        240 
ITKLKTGFGT GGWQLAALRM CSKVASKPLI ADGGIRHNGD IAKSVRFGAS MVMIGSMLAG 

       250        260        270        280        290        300 
HEESPGNVIK IDGKTFKQYW GSASEVQKGA YKNVEGKQML VPYRGSIKDT LREMQEDLQS 

       310        320        330 
AISYAGGREL NSIKLVDYVI VKDNIFDGDK
Q5FHY3 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!