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UniProtKB/Swiss-Prot entry Q5E840

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_VIBF1
Primary accession number Q5E840
Secondary accession numbers None
Integrated into Swiss-Prot on September 13, 2005
Sequence was last modified on March 15, 2005 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 23)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: VF_0311
From
Vibrio fischeri (strain ATCC 700601 / ES114) [TaxID: 312309] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Aliivibrio.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0409900102; PubMed=15703294 [NCBI, ExPASy, EBI, Israel, Japan]
Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P.;
"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners.";
Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000020; AAW84806.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_203694.1; -.
3D structure databases
ModBase Q5E840.
Enzyme and pathway databases
BioCyc VFIS312309:VF0311-MON; -.
Ontologies
GO
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0019344; Biological process: cysteine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS Q5E840.
ProtoNet Q5E840.
Genome annotation databases
GeneID 3277269; -.
GenomeReviews CP000020_GR; VF_0311.
KEGG vfi:VF0311; -.
NMPDR fig|312309.3.peg.311; -.
Phylogenomic databases
HOGENOM Q5E840; -.
Genome annotation databases
CMR Q5E840; VF_0311.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   576  576     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000199913
METAL   439   439        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   445   445        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   485   485        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   489   489        Iron (siroheme axial ligand) (By similarity). 
METAL   489   489        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 576 AA [This is the length of the unprocessed precursor] Molecular weight: 64631 Da [This is the MW of the unprocessed precursor] CRC64: DEC6E859BAF9FD3C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSELIDVKTI LSGTELGPLA DNERLKRESK YLRGTIVEDL QDRITGGFTK DNFQLIRFHG 

        70         80         90        100        110        120 
MYQQDDRDIR AERAKQKLEP LHNVMLRARM PGGIITPKQW LAIDKFAEEH TSYGSLRLTT 

       130        140        150        160        170        180 
RQTFQFHGVL KPNIKLMHQT LNSIGIDSIA TAGDVNRNVL CTTNPVESEL HQEAYEWAKK 

       190        200        210        220        230        240 
ISEHLLPKTR AYAEIWLDGE KLETTDEEPI LGSNYLPRKF KTTVVIPPQN DVDVHANDLN 

       250        260        270        280        290        300 
FIAIADNGKL VGFNVLVGGG LAMTHGDTAT YPRKADDFGF VPLDKTLDVA AAVVTTQRDW 

       310        320        330        340        350        360 
GNRSNRKNAK TKYTLDRVGS DVFKGEVEKR AGVQFEKSRP YELTERGDRI GWVEGIDGKH 

       370        380        390        400        410        420 
HLALFIENGR LLDYPGKPLK TGVAEIAKVH QGDFRMTANQ NLIVAGVPSE QKDHIEQIAR 

       430        440        450        460        470        480 
AHGLIDDTHS EQRKNSMACV AFPTCPLAMA EAERFLPEFV TEIEGVLKKH NLPEEDNIIF 

       490        500        510        520        530        540 
RVTGCPNGCG RAMLAEIGLV GKAPGRYNFH LGGNRSGTRV PKMYKENITD RQILTEIDQL 

       550        560        570 
VGRWATERNE NEGFGDFTIR AGIVDEVKVS KRDFHA
Q5E840 in FASTA format

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