ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q5AW75

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name JHD1_EMENI
Primary accession number Q5AW75
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on April 26, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 23)
Name and origin of the protein
Protein name JmjC domain-containing histone demethylation protein 1
Synonyms EC 1.14.11.27
[Histone-H3]-lysine-36 demethylase 1
Gene name
Name: jhd1
ORFNames: AN7455
From
Emericella nidulans (Aspergillus nidulans) [TaxID: 162425] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; Emericella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=FGSC 4;
DOI=10.1038/nature04341; PubMed=16372000 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L., Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
"Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.";
Nature 438:1105-1115(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AACD01000129; EAA62035.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_680724.1; -.
3D structure databases
ModBase Q5AW75.
Family and domain databases
InterPro IPR013129; TF_JmjC.
IPR003347; TF_JmjC_AAH.
IPR001965; Znf_PHD.
IPR013083; Znf_RING/FYVE/PHD.
Graphical view of domain structure.
Gene3D G3DSA:3.30.40.10; Znf_RING/FYVE/PHD; 1.
Pfam PF02373; JmjC; 1.
PF00628; PHD; 1.
Pfam graphical view of domain structure.
SMART SM00558; JmjC; 1.
SM00249; PHD; 1.
SMART graphical view of domain structure.
PROSITE PS51184; JMJC; 1.
PS01359; ZF_PHD_1; 1.
PS50016; ZF_PHD_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q5AW75.
Genome annotation databases
GeneID 2869726; -.
KEGG ani:AN7455.2; -.
Other
ProtoNet Q5AW75.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chromatin regulator; Dioxygenase; Iron; Metal-binding; Nucleus; Oxidoreductase; Transcription; Transcription regulation; Zinc; Zinc-finger.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   1407  1407     JmjC domain-containing histone demethylation protein 1. PRO_0000226797
DOMAIN   577    735  159     JmjC. 
ZN_FING   323    382  60     PHD-type. 
METAL   631    631        Iron; catalytic (By similarity). 
METAL   633    633        Iron; catalytic (By similarity). 
METAL   703    703        Iron; catalytic (By similarity). 
BINDING   628    628        Substrate (By similarity). 
BINDING   648    648        Substrate (By similarity). 
Sequence information
Length: 1407 AA [This is the length of the unprocessed precursor] Molecular weight: 156107 Da [This is the MW of the unprocessed precursor] CRC64: CE85B1C78A76A2D0 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MISATSFVTA IGSRPPRYRT PSPPRRAVEP ISPCSTADYR TYRASREISA SATSDHVRST 

        70         80         90        100        110        120 
PTDKRPSPAD VPASHRSGHG RSSSTIDTLA TIALATSPTF TPLTHRPPSD KSNTTLSMFP 

       130        140        150        160        170        180 
PETEPVERPA KRPRSERDES SYTQHRSNAF SIARPPAISD SMKTDAELLL NFARPTNLYP 

       190        200        210        220        230        240 
PIPSSKRANT DDSYHNHTFH TQAQIKERNA STYWVTNHEN VIFNHSAMHN IPPSRMRSQS 

       250        260        270        280        290        300 
DGSAAISRPV IEGLRPNTSS STLPPLAFQE EADSGDRHWD MERKPVLEES QVDFCKPDET 

       310        320        330        340        350        360 
VPILSQSQPL KKELDADSNG SSQASCATCN LVRIPVDNED QDVTWISCDG CKRWFHIVCA 

       370        380        390        400        410        420 
GFKNDRETRT VDKFICKTCR PIHGQTTFVR KSSRVRTSID YAGLNQGLVK SATDSLEHHY 

       430        440        450        460        470        480 
IEPIKQNKIR FLPENFPRMR PELVTAEYFE KGNGMTEPIV IPAEFNTHAT IPPTNPEFDA 

       490        500        510        520        530        540 
LVQDAPSQEM FDELLDHLPN VDHETVIDCG QNQLDMVIPQ GLTVRTVSEL YGPEERVEVI 

       550        560        570        580        590        600 
DVKSQHGEDK RWTMQKWADY YESTGDKVVR NVISLEVSQS KLGRLIRRPK IVRDLDLQDA 

       610        620        630        640        650        660 
VWPEELKAVG NFPKVQFYCL MSVADCYTDF HIDFGGSSVY YHILKGKKTF FFIPPKDKHL 

       670        680        690        700        710        720 
KKYEEWCNSP AQDYTFLGDQ TKECYRVDLS EGDTMLIPSG WIHAVWTPEN SLVIGGNFLT 

       730        740        750        760        770        780 
RLNYGMQIKI AKIEKETKVP MKFRYPFFQK IQWYAVLKYL EEDPVPQSVL AAFSQDENYR 

       790        800        810        820        830        840 
FHRKYPIYYE FGERANTEPK GSPYHNSRFY SQAELEGLPD LAKYLLRTAL IAGSYLVEGV 

       850        860        870        880        890        900 
TADTRNAVKR SIPAMPGEPI DVIRTFGVWI AWKRGNEKAA HWTRPGVVES NAKLSLAEKR 

       910        920        930        940        950        960 
PAGRPSRRSE RNADNQRTYA ERQAVQRLSE RPAVDIQKDS APGDESVAPL ANNSPPAATS 

       970        980        990       1000       1010       1020 
GIPVPVMNED TSQKHKTASR GSGLGPKRVA CDACRKRRIR CHHKEENNGA SGSQMTVSTS 

      1030       1040       1050       1060       1070       1080 
SLGHHTPTAQ DAASALNSLA AIASGAGFQN GLHSIKGMDR MDASANFATS ISATPHGVTL 

      1090       1100       1110       1120       1130       1140 
KVGDGSPDGL NSAKKGRSKA CDDCRKSKRR CIHDEYGRID PIKAQERSKP RATSLAKRPR 

      1150       1160       1170       1180       1190       1200 
VHEEAAPSSA NKRLKQESTS PVAQPVHSSH MDTETPTRAQ DSVENGVLDQ YPRKSNTQHA 

      1210       1220       1230       1240       1250       1260 
DGLPAEKALL PDQSSYASPP AFQADAVATK ELPATVSKPA AVLVSPPTSL ADEMDIHDQV 

      1270       1280       1290       1300       1310       1320 
DAGGEHVSVI YTPSSGSRQS SRQPRQVERY MPEVHFAKTA KSTTTTPQTT RRSSFGSSGR 

      1330       1340       1350       1360       1370       1380 
KTTPGLSSGS KKSGSRPSSS HGKKSLSPSV EKKAERHAIS SAPFGQHGRG SKSEHGTSDV 

      1390       1400 
DPDAESLRLI REIQEQEFGL RRRAGRA
Q5AW75 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by kr flag YPRC Korea Mirror sites: Australia Brazil Canada China Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!