NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 13543 / NRRL B-3784;
Dickins M.A., Dhawan T., Gunsalus R.P., Schroeder I., Cecchini G.;
"Cloning, sequencing, and expression of the succinate-ubiquinone oxidoreductase (SdhCDAB) operon from Paracoccus denitrificans.";
Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Succinate + acceptor = fumarate + reduced acceptor.
COFACTOR: Binds 1 2Fe-2S cluster (By similarity).
COFACTOR: Binds 1 3Fe-4S cluster (By similarity).
COFACTOR: Binds 1 4Fe-4S cluster (By similarity).
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle .
SUBUNIT: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein.
SIMILARITY: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
SIMILARITY: Contains 1 2Fe-2S ferredoxin-type domain.
SIMILARITY: Contains 1 4Fe-4S ferredoxin-type domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U31902; AAA75178.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

T46881; T46881.

3D structure databases

HSSP

P07014; 1NEK. [HSSP ENTRY / PDB]

ModBase

Q59662.

Family and domain databases

InterPro

IPR006058; 2Fe2S_fd_BS.
IPR001450; 4Fe4S_Fe_S_bd.
IPR012675; b-grasp_ferredoxin-like.
IPR001041; Ferredoxin.
IPR012285; Fum_reductase_C.
IPR004489; Succ_DHase/fum_Rdtase_Fe-S.
Graphical view of domain structure.

Gene3D

G3DSA:3.10.20.30; Ferredoxin_fold; 1.
G3DSA:1.10.1060.10; Fum_reductase_C; 1.

TIGRFAMs

TIGR00384; dhsB; 1.

PROSITE

PS00197; 2FE2S_FER_1; 1.
PS51085; 2FE2S_FER_2; 1.
PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 1.
PROSITE graphical view of domain structure (profiles).

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

2Fe-2S; 3Fe-4S; 4Fe-4S; Electron transport; Iron; Iron-sulfur; Metal-binding; Oxidoreductase; Transport; Tricarboxylic acid cycle.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 259`	`259`	`Succinate dehydrogenase iron-sulfur subunit.`	`PRO_0000158689`
`DOMAIN`	`28 119`	`92`	`2Fe-2S ferredoxin-type.`
`DOMAIN`	`160 190`	`31`	`4Fe-4S ferredoxin-type.`
`METAL`	`80 80`		`Iron-sulfur 1 (2Fe-2S) (By similarity).`
`METAL`	`85 85`		`Iron-sulfur 1 (2Fe-2S) (By similarity).`
`METAL`	`88 88`		`Iron-sulfur 1 (2Fe-2S) (By similarity).`
`METAL`	`100 100`		`Iron-sulfur 1 (2Fe-2S) (By similarity).`
`METAL`	`170 170`		`Iron-sulfur 2 (4Fe-4S) (By similarity).`
`METAL`	`173 173`		`Iron-sulfur 2 (4Fe-4S) (By similarity).`
`METAL`	`176 176`		`Iron-sulfur 2 (4Fe-4S) (By similarity).`
`METAL`	`180 180`		`Iron-sulfur 3 (3Fe-4S) (By similarity).`
`METAL`	`227 227`		`Iron-sulfur 3 (3Fe-4S) (By similarity).`
`METAL`	`233 233`		`Iron-sulfur 3 (3Fe-4S) (By similarity).`
`METAL`	`237 237`		`Iron-sulfur 2 (4Fe-4S) (By similarity).`

Sequence information

Length: 259 AA [This is the length of the unprocessed precursor]

Molecular weight: 29551 Da [This is the MW of the unprocessed precursor]

CRC64: F70C21BBA8205B4F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MVQLTLPKNS RMRVGKTWPK PEGATNVRRF NIYRWDPDTG ENPRIDTYFV DMDKCGPMVL 

        70         80         90        100        110        120 
DALIKIKNEI DPTLTFRRSC REGICGSCAM NIDGGNHLAC IYGMDEIKGD VNIYPLPHMP 

       130        140        150        160        170        180 
VVKDLVPDLT HFYAQHASVQ PYLITETPTP DKEWRQSIED RKKLDGLYEC VMCASCSTAC 

       190        200        210        220        230        240 
PSYWWNGDRY LGPAALLHAY RWIIDSRDEA TGERLDSLED PFKLYRCHTI MNCTNTCPKG 

       250 
LNPAKAIASI KHMMVDRIV

Q59662 in FASTA format

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View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools