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UniProtKB/Swiss-Prot entry Q56317


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PORB_THEMA
Primary accession number Q56317
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    September 2, 2008 (Entry version 55)
Name and origin of the protein
Protein name Pyruvate synthase subunit porB
Synonyms EC 1.2.7.1
Pyruvate oxidoreductase beta chain
POR
Pyruvic-ferredoxin oxidoreductase subunit beta
Gene name
Name: porB
OrderedLocusNames: TM_0018
From
Thermotoga maritima [TaxID: 2336] [HAMAP proteome]
Taxonomy Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-17 AND 20-44.
STRAIN=ATCC 43589 / MSB8 / DSM 3109 / JCM 10099;
PubMed=8550425 [NCBI, ExPASy, EBI, Israel, Japan]
Kletzin A., Adams M.W.W.;
"Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima.";
J. Bacteriol. 178:248-257(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43589 / MSB8 / DSM 3109 / JCM 10099;
DOI=10.1038/20601; PubMed=10360571 [NCBI, ExPASy, EBI, Israel, Japan]
Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.;
"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima.";
Nature 399:323-329(1999).
Comments
  • CATALYTIC ACTIVITY: Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
  • SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma chain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X85171; CAA59458.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE000512; AAD35112.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B59427; D72427.
RefSeq NP_227834.1; -.
3D structure databases
HSSP P94692; 1KEK. [HSSP ENTRY / PDB]
ModBase Q56317.
Enzyme and pathway databases
BioCyc MetaCyc:MON-424; -.
TMAR243274:TM_0018-MON; -.
Family and domain databases
InterPro IPR011766; TPP_enzyme_bd_C.
Graphical view of domain structure.
Pfam PF02775; TPP_enzyme_C; 1.
Pfam graphical view of domain structure.
BLOCKS Q56317.
Genome annotation databases
GeneID 896832; -.
GenomeReviews AE000512_GR; TM_0018.
KEGG tma:TM0018; -.
NMPDR fig|243274.1.peg.18; -.
TIGR TM_0018; -.
Phylogenomic databases
HOGENOM Q56317; -.
Other
ProtoNet Q56317.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Direct protein sequencing; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   324  323     Pyruvate synthase subunit porB. PRO_0000099909
Sequence information
Length: 324 AA [This is the length of the unprocessed precursor] Molecular weight: 36385 Da [This is the MW of the unprocessed precursor] CRC64: 2425239D778A6A0E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MPVNIKQLAQ EFDKKEIGIT QGHRLCPGCG APITVKFVMM IARHLGYEPV VGLATGCLEV 

        70         80         90        100        110        120 
STSIYPYTAW SVPYIHNAFE NVAATMSGVE TAYKALKNKG KIPEDKKYAF IAFGGDGGTY 

       130        140        150        160        170        180 
DIGLQSLSGM LERGHKVLYV LYDNEGYMNT GNQRSGSTPP GSDTTTAPVG KKLPGKVQLK 

       190        200        210        220        230        240 
KNIVEIVAAH ENVYAATASL SEPMDFFAKV EKALNFDGPS FLAVFSPCVR FWRVNDDKTV 

       250        260        270        280        290        300 
EISKLAVETK YWPLYEVERG VYRVTRKPRQ FKPVEEFLKA QGRFRKLLSR PDAKEIVDEL 

       310        320 
QEYVDRRWER LLTLEEVTKD KPIR 

Q56317 in FASTA format

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