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UniProtKB/Swiss-Prot entry Q54JE4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ODO1_DICDI
Primary accession number Q54JE4
Secondary accession numbers None
Integrated into Swiss-Prot on April 8, 2008
Sequence was last modified on May 24, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 26)
Name and origin of the protein
Protein name 2-oxoglutarate dehydrogenase E1 component, mitochondrial [Precursor]
Synonyms EC 1.2.4.2
Alpha-ketoglutarate dehydrogenase
Gene name
Name: ogdh
ORFNames: DDB_0234117
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAFI02000109; EAL63408.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_636906.1; -.
3D structure databases
ModBase Q54JE4.
Organism-specific databases
dictyBase DDB0234117; ogdh.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
QuickGo view.
Family and domain databases
InterPro IPR011603; 2oxoglutarate_DHase_E1.
IPR001017; DHase_E1.
IPR005475; Transketo_Cen_R.
Graphical view of domain structure.
PANTHER PTHR23152; 2oxoglutarate_DH_E1; 1.
Pfam PF00676; E1_dh; 1.
PF02779; Transket_pyr; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000157; Oxoglu_dh_E1; 1.
TIGRFAMs TIGR00239; 2oxo_dh_E1; 1.
BLOCKS Q54JE4.
Genome annotation databases
GeneID 3388479; -.
KEGG ddi:DDB_0234117; -.
Other
ProtoNet Q54JE4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Mitochondrion; Oxidoreductase; Thiamine pyrophosphate; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
TRANSIT   1     39  39     Mitochondrion (Potential). 
CHAIN   40   1013  974     2-oxoglutarate dehydrogenase E1 component, mitochondrial. PRO_0000328590
Sequence information
Length: 1013 AA [This is the length of the unprocessed precursor] Molecular weight: 114068 Da [This is the MW of the unprocessed precursor] CRC64: CE908E70E8394632 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFTLKQVINK SIQTSMKNGV MSSAVKRSFS TVGGINQPKS RKELSESFLD GTSSTYVEDM 

        70         80         90        100        110        120 
FANWVKDPKS VHPSWASFFE SSERGVPAGE AFMSPPTLGS SVATKATPST YTSSGSPKQV 

       130        140        150        160        170        180 
SDSMRLLLLV RAYQVRGHAL ANLDPLGLEV KEEPAEFNPA KYGFTEADMD RPIFVGEGFI 

       190        200        210        220        230        240 
SGFLTNKQPE TTLRQVLKRL KETYCGDIGI EYMHIQDREM CDWIRDKFET SQPVEIPDKE 

       250        260        270        280        290        300 
KIKILERLSW ADQFEGFLGL KYRATRRFGL DGCESLIPGM KAMIDTATED GVESIVLGMP 

       310        320        330        340        350        360 
HRGRLNVLAN VVRKPLPAIF NEFNGGVISI EGEYSATGDV KYHLGTSYDR VTSSGKKVHL 

       370        380        390        400        410        420 
SLVANPSHLE AVNPLVEGKV RAKQHYSKDT EQKKSMAVQL HGDASVAGQG VVYETLHLSN 

       430        440        450        460        470        480 
LDNYSTGGTV HIVVNNQIGF TTNPKYSRSS KYCTDVAKTI DIPVFHVNGD NVEAVVKVCK 

       490        500        510        520        530        540 
IAAEWRQKFK RDVFVDIVCY RKHGHNETDQ PKFTQPIMYD KIGKQQPIIE KYSNKLIAEK 

       550        560        570        580        590        600 
VITQEQYLQM KNIIHESYEK GYQDGMKHVP NAEDWLESRW EGFKSPIELG NPGRTGIDQD 

       610        620        630        640        650        660 
LLQKIGKVLY TEPSGFEVHS TIKRLLKEKK DMFDKGTGFD WATAEALAFG SLLLDGNHVR 

       670        680        690        700        710        720 
LSGQDVERGT FSHRHAVWHD QKTDQTYAPL TKLATALGKK DAAEFVASNS SLSEFAVLGF 

       730        740        750        760        770        780 
ELGYSLENPD ALILWEAQFG DFSNGAQVII DQFISSGEQK WMRQSGLTML LPHGYDGAGP 

       790        800        810        820        830        840 
EHSSCRIERY LQLCDSDPNK IPPKEEAERK QSQHCNMQVL NCSTPVNYFH ALRRQVHRDF 

       850        860        870        880        890        900 
RKPLVIATPK YLLRYEKSFS TAKEFSNDSF TRLYPEAFPD QINKPEKINR IVFCTGQVYY 

       910        920        930        940        950        960 
NLIASRESNN IKDVAIIRVE QLHPFPFDLV AEQLQHYPNA KAIWCQEEPM NMGYWNYIYP 

       970        980        990       1000       1010 
YFISTFKHIN RPADITYTGR PSSASPAVAS HTLHKLQLEN FLSNALTGQV GSK 

Q54JE4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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