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UniProtKB/Swiss-Prot entry Q54IL7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR1_DICDI
Primary accession number Q54IL7
Secondary accession numbers None
Integrated into Swiss-Prot on April 8, 2008
Sequence was last modified on May 24, 2005 (Sequence version 1)
Annotations were last modified on    September 23, 2008 (Entry version 22)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase 1
Synonyms P5C reductase 1
P5CR 1
EC 1.5.1.2
Gene name
Name: pycr1
ORFNames: DDB_0232206
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAFI02000119; EAL63112.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_636614.1; -.
3D structure databases
ModBase Q54IL7.
Organism-specific databases
dictyBase DDB0232206; pycr1.
Family and domain databases
InterPro IPR016040; NAD(P)-bd.
IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
BLOCKS Q54IL7.
Genome annotation databases
GeneID 3388184; -.
KEGG ddi:DDB_0232206; -.
Other
ProtoNet Q54IL7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   551  551     Pyrroline-5-carboxylate reductase 1. PRO_0000328304
COMPBIAS   297   388  92     His-rich. 
COMPBIAS   319   326  8     Poly-Gln. 
COMPBIAS   448   453  6     Poly-Gln. 
COMPBIAS   456   474  19     Poly-Gln. 
COMPBIAS   487   496  10     Poly-Gln. 
COMPBIAS   504   532  29     Asn-rich. 
Sequence information
Length: 551 AA [This is the length of the unprocessed precursor] Molecular weight: 63009 Da [This is the MW of the unprocessed precursor] CRC64: 6D15ED4680D6244D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKLYDNGVAV LGCGNLGNAI AKGLVASKQF KSNQIVLTKR NLSTIEPLKR EGYHVTTSNH 

        70         80         90        100        110        120 
DAVSRCKIVI VCVVPAQLDD LLDSIKQSVT ENHIIISVVS GASIEDIRSH LEKDVPIVRA 

       130        140        150        160        170        180 
MPNTAIQHCQ SMTCLAIRSS HQKSTNSPSD KAKDNALEVA KKIFNCLGMS IVLSEEQIVP 

       190        200        210        220        230        240 
ATALCACGIA FFCRAIRAAA QGGCEIGFHA EDAIRIAAQT AKGAATLLLE NNFHPEYEID 

       250        260        270        280        290        300 
KVTTPQGCTI AGLNQMEHAG FSSAMIKGIV TSSDKAASLY TQKQQNKKQQ QLKQQQHQQH 

       310        320        330        340        350        360 
QHQQHQQHQQ QVQQQEPHQY QQQQQQSHQQ SQYNQGHNYG HQNQHHHNHD DQHQNYYNQD 

       370        380        390        400        410        420 
QKRRNNRKHR SNENYDNHHH HNQQYQQHQQ PTQQESQEQT QQPEQTQSTN QSNQRRNSES 

       430        440        450        460        470        480 
RNGKSPQKQP QKQSQVQQPS STTENTDQQQ QQQPPQEQQQ QQEQPQQPQE QQQQPNVVDE 

       490        500        510        520        530        540 
AERPKEQQQQ PQQQQQTIDK KGYNNNRRGG RHYSYNNNYN SHHHRHNGIN KNSSSMYHDE 

       550 
KRHEVKTEQI N 

Q54IL7 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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