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UniProtKB/Swiss-Prot entry Q51802


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name VORB_PYRFU
Primary accession number Q51802
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 48)
Name and origin of the protein
Protein name Ketoisovalerate oxidoreductase subunit vorB
Synonyms VOR
EC 1.2.7.7
2-oxoisovalerate oxidoreductase beta chain
2-oxoisovalerate ferredoxin reductase subunit beta
Gene name
Name: vorB
OrderedLocusNames: PF0968
From
Pyrococcus furiosus [TaxID: 2261] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-7.
STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
PubMed=8550425 [NCBI, ExPASy, EBI, Israel, Japan]
Kletzin A., Adams M.W.W.;
"Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima.";
J. Bacteriol. 178:248-257(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
Weiss R.B., Dunn D.M., Robb F.T., Brown J.R.;
"The complete sequence of the Pyrococcus furiosus genome.";
Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
Comments
  • CATALYTIC ACTIVITY: 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.
  • SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma chain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X85250; CAA59503.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE010209; AAL81092.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T45086; T45086.
RefSeq NP_578697.1; -.
3D structure databases
HSSP P94692; 1KEK. [HSSP ENTRY / PDB]
ModBase Q51802.
Family and domain databases
InterPro IPR011766; TPP_enzyme_bd_C.
Graphical view of domain structure.
Pfam PF02775; TPP_enzyme_C; 1.
Pfam graphical view of domain structure.
BLOCKS Q51802.
Genome annotation databases
GeneID 1468833; -.
GenomeReviews AE009950_GR; PF0968.
KEGG pfu:PF0968; -.
NMPDR fig|186497.1.peg.1004; -.
Phylogenomic databases
HOGENOM Q51802; -.
Genome annotation databases
CMR Q51802; PF0968.
Other
ProtoNet Q51802.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Direct protein sequencing; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   311  311     Ketoisovalerate oxidoreductase subunit vorB. PRO_0000099957
Sequence information
Length: 311 AA [This is the length of the unprocessed precursor] Molecular weight: 34766 Da [This is the MW of the unprocessed precursor] CRC64: 07CC02452E3C6074 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEVPENIKKR VTIPFEEHFY AGHTACQGCG ASLGLRYVLK AYGKKTILVI PACCSTIIAG 

        70         80         90        100        110        120 
PWPYSAIDAN LFHTAFETTG AVISGIEAAL KAMGYKVKGE DGIMVVGWAG DGGTADIGLQ 

       130        140        150        160        170        180 
ALSGFLERGH DAVYIMYDNE AYMNTGIQRS SSTPYGAWTT NTPGGRRHFL EKRHKKKVID 

       190        200        210        220        230        240 
IVIAHRIPYA ATASIAYPED FIRKLKKAQK ISGPSFIQLF APCPTGWRAP TDKSIEIARL 

       250        260        270        280        290        300 
AVQTAYFPLF EYENGKYKIN MPNPKKEPKP IEEFLKLQGR FKYMTKEDIE TLQKWVLEEW 

       310 
ERLKKLAEVF G 

Q51802 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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