[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. PubMed=9202457 [NCBI, ExPASy, EBI, Israel, Japan] Gak E.R., Tsygankov Y.D., Chistoserdov A.Y.; "Organization of methylamine utilization genes (mau) in 'Methylobacillus flagellatum ' KT and analysis of mau mutants."; Microbiology 143:1827-1835(1997).
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N., Anderson I., Richardson P.; "Complete sequence of Methylobacillus flagellatus KT."; Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
[3]	NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-68 AND 332-400. PubMed=7635847 [NCBI, ExPASy, EBI, Israel, Japan] Gak E.R., Chistoserdov A.Y., Lidstrom M.E.; "Cloning, sequencing, and mutation of a gene for azurin in Methylobacillus flagellatum KT."; J. Bacteriol. 177:4575-4578(1995).

Comments

FUNCTION: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
CATALYTIC ACTIVITY: RCH₂NH₂ + H₂O + acceptor = RCHO + NH₃ + reduced acceptor.
SUBUNIT: Tetramer of two light and two heavy chains.
SUBCELLULAR LOCATION: Periplasm.
SIMILARITY: Belongs to the aromatic amine dehydrogenase heavy chain family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF188997; AAC41469.2; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
CP000284; ABE48818.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_544659.1; -.

3D structure databases

HSSP

P29894; 2MTA. [HSSP ENTRY / PDB]

ModBase

Q50420.

Enzyme and pathway databases

BioCyc

MFLA265072:MFLA_0548-MON; -.

Ontologies

GO:0042597;	Cellular component: periplasmic space (inferred from electronic annotation from InterPro).
GO:0030058;	Molecular function: amine dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0022900;	Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0030416;	Biological process: methylamine metabolic process (inferred from electronic annotation from InterPro).
GO:0006810;	Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR013476; MeN_DHase_hvc.
IPR009451; Metamine_DHase_Hsu.
IPR015943; WD40/YVTN_repeat-like.
Graphical view of domain structure.

Gene3D

G3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1.

Pfam

PF06433; Me-amine-dh_H; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF017797; TTQ_MADH_Hv; 1.

TIGRFAMs

TIGR02658; TTQ_MADH_Hv; 1.

Genome annotation databases

GeneID

4000887; -.

GenomeReviews

CP000284_GR; Mfla_0548.

KEGG

mfa:Mfla_0548; -.

NMPDR

fig|265072.7.peg.546; -.

Phylogenomic databases

HOGENOM

Q50420; -.

Genome annotation databases

CMR

Q50420; Mfla_0548.

Other

ProtoNet

Q50420.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Electron transport; Oxidoreductase; Periplasm; Signal; Transport.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 27`	`27`	`Potential.`
`CHAIN`	`28 400`	`373`	`Methylamine dehydrogenase heavy chain.`	`PRO_0000025578`

Sequence information

Length: 400 AA [This is the length of the unprocessed precursor]

Molecular weight: 44330 Da [This is the MW of the unprocessed precursor]

CRC64: 6ACCF91ADF6979B6 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTTFQPGRLA GQLAATALLA ATCSAFAADA PTTVPSSLGA IGTTPTLDNI TMEPGLPSDA 

        70         80         90        100        110        120 
KRVYVLDPGH FHVTTTVYTI DGNKNNLLGM TDTGKLANVM LSSDGKFFVT SNTTYSRIAR 

       130        140        150        160        170        180 
GKRDDYVEVI DAQSHKVLAD IDIPEGRFLT GVMNRMASLS TDNKYMLFQQ FAPSPAVGLV 

       190        200        210        220        230        240 
DLEKKSFVKM MDIPDCYQIF PVPNQSFYMH CRDGSLQQFG YDDKGNLKPM KPTKVFHGED 

       250        260        270        280        290        300 
DYLFVNPYYS NGSGRLVWPT YEGRIFQAKL TDKKVDFMKP FELFTEAEKK ANWRPGGWQV 

       310        320        330        340        350        360 
VAYHKARNEI YVLADQRAKW THVTASRYVF VVDGTTGKRL RRIDLGHEID GISVTQDANP 

       370        380        390        400 
NLYAVSAEAK TLFTFNAVTG KETGKVDELG RAPTISLTMD

Q50420 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools