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UniProtKB/Swiss-Prot entry Q4WHB7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name JHD1_ASPFU
Primary accession number Q4WHB7
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on July 5, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 26)
Name and origin of the protein
Protein name JmjC domain-containing histone demethylation protein 1
Synonyms EC 1.14.11.27
[Histone-H3]-lysine-36 demethylase 1
Gene name
Name: jhd1
ORFNames: AFUA_2G05970
From
Aspergillus fumigatus (Sartorya fumigata) [TaxID: 5085] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Af293 / CBS 101355 / FGSC A1100;
DOI=10.1038/nature04332; PubMed=16372009 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.;
"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.";
Nature 438:1151-1156(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAHF01000008; EAL87688.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_749726.1; -.
3D structure databases
ModBase Q4WHB7.
Family and domain databases
InterPro IPR013129; TF_JmjC.
IPR003347; TF_JmjC_AAH.
IPR001965; Znf_PHD.
IPR013083; Znf_RING/FYVE/PHD.
Graphical view of domain structure.
Gene3D G3DSA:3.30.40.10; Znf_RING/FYVE/PHD; 1.
Pfam PF02373; JmjC; 1.
PF00628; PHD; 1.
Pfam graphical view of domain structure.
SMART SM00558; JmjC; 1.
SM00249; PHD; 1.
SMART graphical view of domain structure.
PROSITE PS51184; JMJC; 1.
PS01359; ZF_PHD_1; 1.
PS50016; ZF_PHD_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q4WHB7.
Genome annotation databases
GeneID 3506876; -.
KEGG afm:AFUA_2G05970; -.
Phylogenomic databases
HOGENOM Q4WHB7; -.
Other
ProtoNet Q4WHB7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chromatin regulator; Complete proteome; Dioxygenase; Iron; Metal-binding; Nucleus; Oxidoreductase; Transcription; Transcription regulation; Zinc; Zinc-finger.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   1418  1418     JmjC domain-containing histone demethylation protein 1. PRO_0000226792
DOMAIN   588    746  159     JmjC. 
ZN_FING   331    391  61     PHD-type. 
METAL   642    642        Iron; catalytic (By similarity). 
METAL   644    644        Iron; catalytic (By similarity). 
METAL   714    714        Iron; catalytic (By similarity). 
BINDING   639    639        Substrate (By similarity). 
BINDING   659    659        Substrate (By similarity). 
Sequence information
Length: 1418 AA [This is the length of the unprocessed precursor] Molecular weight: 157353 Da [This is the MW of the unprocessed precursor] CRC64: 5575A6C161A1C82C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MIGATSFLNH SGPRPPRYRT PSPPRRAVEP ISPFTTTTDF RASWIDRGDS QAASYDRDRV 

        70         80         90        100        110        120 
TSNNDVYSST NRGSHGRTSH GRSSSTIDTL ATIALATSPT FAPLSYRPPS QDPTPAMPLF 

       130        140        150        160        170        180 
PSQSIESTER PAKRPRSEKS PSPLHQPQTT VAPDANPSST FDSMKTDAEL LLNFARPSNF 

       190        200        210        220        230        240 
QPAAFYPSKR VSIDESYHPH YGEEPKSHFR AGLGSTYILP DGEKSAYHTS ANTAFPASRM 

       250        260        270        280        290        300 
RSQSDGSAFI SRPVIQGVRP NTSSSTLPPI VWQEEEGNAK TGPGPPSTKF PGAETRYENS 

       310        320        330        340        350        360 
VFTGIDTGAD RASLDVPPRG DDDTESDENN QANCAACNLV RIPVDSEEQG DVTWISCDGC 

       370        380        390        400        410        420 
KQWFHIVCAG FKNDREIRTV DKFICRRCRP IHGQTTFVRK SSRARTAIDY AGLNQGLVKA 

       430        440        450        460        470        480 
ASDSLEHHYI EPIREGKIRF LPDNFPRMRP ELVTAEYFER GSGMTEPIVI PAHLNTRDSI 

       490        500        510        520        530        540 
PIVDPEFDSL VQEATSQEMF DELLEHLPEE GKDFETVIDC GQDQLDMVVP QGLTVRAVAE 

       550        560        570        580        590        600 
LYGPEERVEV IDVKSQQGED KRWNMQKWAD YYESTGSKVV RNVISLEVSQ SKLGKLIRRP 

       610        620        630        640        650        660 
KIVRDLDLQD AVWPEELKAI GDYPKVQFYC LMSVADCYTD FHIDFGGSSV YYHILKGKKT 

       670        680        690        700        710        720 
FFFIPPKDKH LKKYEDWCNS PAQDSTFLGD QTKECYRVDL SEGDTMLIPS GWIHAVWTPT 

       730        740        750        760        770        780 
NSLVIGGNFL TRLNYGMQIK VAKIEKDTKV PRKFRYPFFQ RIQWYTALKY LEDDPIPQSV 

       790        800        810        820        830        840 
LNAFAEDENY RFHRAYPIYY EFGERENKAP AGDPYHNSRF YSQAELEGLP DLAKYLLRTA 

       850        860        870        880        890        900 
LIASGYMVEG VTMDARNAVK RSIPKGQGDP IDTVRKFGIW VAWKRGNEKA PQWTRPGVVE 

       910        920        930        940        950        960 
SNAKLSLTEK KPAGRPSRRS ERNAEGQRMY AERQAVQRPL EQPPDLTNGL SSEESSSAPS 

       970        980        990       1000       1010       1020 
TVEIPQSTVI STLPGTETKE LKEEIAQKPR SIHRSSGLGP KRVACDACRK RRIRCRHKDE 

      1030       1040       1050       1060       1070       1080 
HNDTISAKQT TFGTFPAGVQ SSLAHDAASA LNSLAAIASE AGFQDAANGH GLERLEGSGN 

      1090       1100       1110       1120       1130       1140 
YSTAILSTPN AATSKVHDGS PEGLNTGKKG RSKACDDCRK SKRRCIHDEY GRIDPIKAQE 

      1150       1160       1170       1180       1190       1200 
RSKPRATASA KRPRPPQEED AAFTLNKRPK QESTSPVARP ASLFRAEGDM SHTQRPVDLE 

      1210       1220       1230       1240       1250       1260 
ASSYFGTAHD HNGIAQTKLT SAVGQTSYAS PPAFQSDTVV MEVAGQGVSK PTASLVSPPT 

      1270       1280       1290       1300       1310       1320 
SQADETDVPP EQDAEKDNHV VYYTPTTSSR HSSRQPRHVD RYVPESQPAK AVKTTHTPSK 

      1330       1340       1350       1360       1370       1380 
RRASCSGPTT ARRVTPGAQG SSKKPASRPS SSHAKKGVSP VTEKKFDRMT TTSTSPGHKG 

      1390       1400       1410 
AKRERTAIAD DEPDAESLRL IRELQEQEFG LRKRTTRV 

Q4WHB7 in FASTA format

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