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UniProtKB/Swiss-Prot entry Q4UM07


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NUOC_RICFE
Primary accession number Q4UM07
Secondary accession numbers None
Integrated into Swiss-Prot on May 15, 2007
Sequence was last modified on July 5, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 22)
Name and origin of the protein
Protein name NADH-quinone oxidoreductase subunit C
Synonyms EC 1.6.99.5
NADH dehydrogenase I subunit C
NDH-1 subunit C
Gene name
Name: nuoC
OrderedLocusNames: RF_0565
From
Rickettsia felis (Rickettsia azadi) [TaxID: 42862] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC VR-1525 / URRWXCal2;
DOI=10.1371/journal.pbio.0030248; PubMed=15984913 [NCBI, ExPASy, EBI, Israel, Japan]
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.;
"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite.";
PLoS Biol. 3:1-12(2005).
Comments
  • FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
  • CATALYTIC ACTIVITY: NADH + quinone = NAD+ + quinol.
  • SIMILARITY: Belongs to the complex I 30 kDa subunit family.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000053; AAY61416.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_246581.1; -.
3D structure databases
ModBase Q4UM07.
Enzyme and pathway databases
BioCyc RFEL315456:RF_0565-MON; -.
Family and domain databases
InterPro IPR010218; NADH_DH_csu.
IPR001268; NADH_DHase_Ub_30kDa_su.
Graphical view of domain structure.
Pfam PF00329; Complex1_30kDa; 1.
Pfam graphical view of domain structure.
ProDom PD001581; Complex1_30K; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01961; NuoC_fam; 1.
PROSITE PS00542; COMPLEX1_30K; FALSE_NEG.
BLOCKS Q4UM07.
Genome annotation databases
GeneID 3400344; -.
GenomeReviews CP000053_GR; RF_0565.
KEGG rfe:RF_0565; -.
NMPDR fig|315456.3.peg.399; -.
Phylogenomic databases
HOGENOM Q4UM07; -.
Genome annotation databases
CMR Q4UM07; RF_0565.
Other
ProtoNet Q4UM07.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase; Quinone.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   207  207     NADH-quinone oxidoreductase subunit C. PRO_0000287859
Sequence information
Length: 207 AA [This is the length of the unprocessed precursor] Molecular weight: 24256 Da [This is the MW of the unprocessed precursor] CRC64: DD092E30E558D59A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTLDKLIEKL AAKSSILITP IIVKDYLAYQ VEPNFLLPFL KALKESEELR FTVLTDLFGT 

        70         80         90        100        110        120 
DFPERDKRFE VIYNLLSLKL NKRLIIKVYI SEKETIPSAM NIFNASCWYE REVYDMYGVN 

       130        140        150        160        170        180 
FDGNDDKRRI LTDYEFEGHP LRKDFPLTGY TQVKYDEKLK KVAYEPVDLD IEYREFDFSS 

       190        200 
HWHSPSYVLP GDEKATDVIP AKAGIQK 

Q4UM07 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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