NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC VR-1525 / URRWXCal2;
DOI=10.1371/journal.pbio.0030248; PubMed=15984913 [NCBI, ExPASy, EBI, Israel, Japan]
Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D.;
"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite.";
PLoS Biol. 3:1-12(2005).

Comments

CATALYTIC ACTIVITY: ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; tetrahydrodipicolinate from L-aspartate: step 1/4 .
PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3 .
PATHWAY: Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5 .
SIMILARITY: Belongs to the aspartokinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000053; AAY62051.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_247216.1; -.

3D structure databases

ModBase

Q4UK84.

Enzyme and pathway databases

BioCyc

RFEL315456:RF_1200-MON; -.

Ontologies

GO:0019877;	Biological process: diaminopimelate biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR001048; Asp/Glu/Uridylate_kinase.
IPR001341; Asp_kin_reg.
IPR001057; Glu_5kinase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.1160.10; Aa_kinase; 1.

Pfam

PF00696; AA_kinase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00474; GLU5KINASE.

TIGRFAMs

TIGR00657; asp_kinases; 1.

PROSITE

PS00324; ASPARTOKINASE; 1.

Genome annotation databases

GeneID

3401498; -.

GenomeReviews

CP000053_GR; RF_1200.

KEGG

rfe:RF_1200; -.

NMPDR

fig|315456.3.peg.1200; -.

Phylogenomic databases

HOGENOM

Q4UK84; -.

Genome annotation databases

CMR

Q4UK84; RF_1200.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Complete proteome; Diaminopimelate biosynthesis; Kinase; Lysine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 401`	`401`		`Aspartokinase.`	`PRO_0000288720`

Sequence information

Length: 401 AA [This is the length of the unprocessed precursor]

Molecular weight: 44340 Da [This is the MW of the unprocessed precursor]

CRC64: 5492DB95BBA62FA0 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MALIIQKFGG TSVANIDRIK KIAPIIKAEI AKNNQVIVVV SAMAGVTNQL VTLCNEVSSL 

        70         80         90        100        110        120 
NNISQFAEYD VALSSGEIVT ASLLALALQE EDIKAQSFLA WQLPILTDNN HSKALVESIT 

       130        140        150        160        170        180 
TDLLEKYLQL NTVPIIAGFQ GTNKSNRLTT LGRGGSDTTA ALIAAAMKAK RCDIYTDVEG 

       190        200        210        220        230        240 
IFTADPRIIP NAKKIKEIDF LEMLELASSG AKVLHPRAVE LVMRYKIDMR VLSTFSPNTE 

       250        260        270        280        290        300 
GTLITSKDKN MENGIINSIT SNKNLLKISV KSISLSFLQV ANMITQNNNH IEFMQEIKNN 

       310        320        330        340        350        360 
EEYSFITNLT DENNLQALLT NLKNDKQIQD FTFDAEIATI SLIGYGIKND CKVLEMILSK 

       370        380        390        400 
LTKDNINVNM IQLSEVKITL LINDQDAEKT IFNLYNLFKI S

Q4UK84 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools