NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.187.21.7292-7308.2005; PubMed=16237012 [NCBI, ExPASy, EBI, Israel, Japan]
Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.;
"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species.";
J. Bacteriol. 187:7292-7308(2005).

Comments

CATALYTIC ACTIVITY: An aldehyde + NAD⁺ + H₂O = an acid + NADH.
SIMILARITY: Belongs to the aldehyde dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP006716; BAE03856.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_252462.1; -.

3D structure databases

ModBase

Q4L919.

Enzyme and pathway databases

BioCyc

SHAE279808:SH0547-MON; -.

Family and domain databases

InterPro

IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.

PANTHER

PTHR11699; Aldehyde_dehyd; 1.

Pfam

PF00171; Aldedh; 1.
Pfam graphical view of domain structure.

PROSITE

PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.

BLOCKS

Q4L919.

Genome annotation databases

3482408; -.

AP006716_GR; SH0547.

sha:SH0547; -.

fig|279808.3.peg.637; -.

Phylogenomic databases

HOGENOM

Q4L919; -.

Genome annotation databases

CMR

Q4L919; SH0547.

Other

ProtoNet

Q4L919.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 497`	`497`	`Putative aldehyde dehydrogenase aldA.`	`PRO_0000056463`
`NP_BIND`	`213 219`	`7`	`NAD (By similarity).`
`ACT_SITE`	`257 257`		`By similarity.`
`ACT_SITE`	`291 291`		`By similarity.`

Sequence information

Length: 497 AA [This is the length of the unprocessed precursor]

Molecular weight: 54119 Da [This is the MW of the unprocessed precursor]

CRC64: 6BBC0B29CBED6B8E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAKVNVRDFI EEQYGLFING EFQASESGDT LTVTNPANGE DLAKVAKASK SDVDKAVQAA 

        70         80         90        100        110        120 
QDAFDSWSKT SKEERADYLL EISRRIHEKV EHFATIESLQ NGKPYRETST IDVPLTANQF 

       130        140        150        160        170        180 
KYFASVLTTD EGSVNEIDEN TMSLVVNEPV GVVGAVVAWN FPILLASWKL APALAAGNTI 

       190        200        210        220        230        240 
VIQPSSSTPL SLIELAKIFQ EVLPKGVVNV LTGKGSESGD AIFNHEGVNK LSFTGSTDVG 

       250        260        270        280        290        300 
YGVAKAGAER IVPTTLELGG KSANIIFDDA NLDQVVEGAQ LGILFNQGEV CSAGSRLLVQ 

       310        320        330        340        350        360 
SSIYDKVMPK LKEAFENIKV GDPFDEDVKM SAQTGPEQLE KIESYVKIAE EDSNANILTG 

       370        380        390        400        410        420 
GHRLTDNGRD KGYFFEPTII EIKDNSHQLA QEEIFGPVVV VEKFEDEAEA IKIANDSEYG 

       430        440        450        460        470        480 
LAGGIFTTNI NRALNVAKAM RTGRIWINTY NQFPAGAPFG GYKKSGIGRE IYKDAIKNYQ 

       490 
QVKNIFIDTS NQTKGLY

Q4L919 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools