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UniProtKB/Swiss-Prot entry Q4KI35

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HGD_PSEF5
Primary accession number Q4KI35
Secondary accession numbers None
Integrated into Swiss-Prot on March 7, 2006
Sequence was last modified on August 2, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 22)
Name and origin of the protein
Protein name Homogentisate 1,2-dioxygenase
Synonyms EC 1.13.11.5
Homogentisicase
Homogentisate oxygenase
Homogentisic acid oxidase
Gene name
Name: hmgA
OrderedLocusNames: PFL_0967
From
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) [TaxID: 220664] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt1110; PubMed=15980861 [NCBI, ExPASy, EBI, Israel, Japan]
Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.A., Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J., Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J., Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C., Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S. III, Thomashow L.S., Loper J.E.;
"Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5.";
Nat. Biotechnol. 23:873-878(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000076; AAY90254.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_258098.1; -.
3D structure databases
ModBase Q4KI35.
Enzyme and pathway databases
BioCyc PFLU220664:PFL_0967-MON; -.
Ontologies
GO
GO:0004411; Molecular function: homogentisate 1,2-dioxygenase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from HAMAP).
GO:0006559; Biological process: L-phenylalanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0006572; Biological process: tyrosine catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00334; -; 1.
PBIL [Tree]
InterPro IPR005708; Homogentis_dOase.
Graphical view of domain structure.
PANTHER PTHR11056; Homogentis_dOase; 1.
Pfam PF04209; HgmA; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01015; hmgA; 1.
BLOCKS Q4KI35.
Genome annotation databases
GeneID 3476741; -.
GenomeReviews CP000076_GR; PFL_0967.
KEGG pfl:PFL_0967; -.
NMPDR fig|220664.3.peg.2411; -.
Phylogenomic databases
HOGENOM Q4KI35; -.
Genome annotation databases
CMR Q4KI35; PFL_0967.
Other
ProtoNet Q4KI35.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   434  434     Homogentisate 1,2-dioxygenase. PRO_0000225791
METAL   332   332        Iron (By similarity). 
METAL   338   338        Iron (By similarity). 
METAL   368   368        Iron (By similarity). 
Sequence information
Length: 434 AA [This is the length of the unprocessed precursor] Molecular weight: 47945 Da [This is the MW of the unprocessed precursor] CRC64: 4C32086AE5EEE7A8 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNLDSSASAL SYQSGFGNEF ASEALPGALP VGQNSPQKAP YGLYAELFSG TAFTMTRSEA 

        70         80         90        100        110        120 
RRTWMYRIQP SAKHPAFAKL ARQLAGGPLG EVTPNRLRWS PLQIPSEPTD FIDGLVAMVA 

       130        140        150        160        170        180 
NSAAQKPAGI SVYHYRANRS MERVFFNADG ELLLVPELGR LRIVTELGML DLEPLEIAVL 

       190        200        210        220        230        240 
PRGLKFRIEL LDPQARGYVA ENHGAPLRLP DLGPIGSNGL ANPRDFLAPV AHYEDLRQPT 

       250        260        270        280        290        300 
TLVQKYLGEL WGCELDHSPL NVVAWHGNNV PYKYDLRRFN TIGTVSFDHP DPSIFTVLTS 

       310        320        330        340        350        360 
PTSVPGLANL DFVIFPPRWM VAENTFRPPW FHRNLMNEFM GLIQGAYDAK AEGFLPGGAS 

       370        380        390        400        410        420 
LHSCMSAHGP DGETCTKAIN AQLQPAKIDN TMAFMFETSQ VLRPSQFALE CPELQNDYDA 

       430 
CWASLPVTFN PNRR
Q4KI35 in FASTA format

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