[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=GJ31; Reineke W., Kunze M.; "GJ31 meta-operon."; Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Catalyzes the terminal reaction in meta-cleavage pathways, that is, the transformation of acetaldehyde into acetyl coenzyme A (By similarity).
CATALYTIC ACTIVITY: Acetaldehyde + CoA + NAD⁺ = acetyl-CoA + NADH.
PATHWAY: Aromatic compound metabolism; 3-phenylpropionic acid degradation .
SIMILARITY: Belongs to the acetaldehyde dehydrogenase family. MhpF subfamily.

Copyright

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Cross-references

Sequence databases

EMBL

AY831461; AAX50131.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

SMR

Q49KG0; 1-312.

ModBase

Q49KG0.

Ontologies

GO:0008774;	Molecular function: acetaldehyde dehydrogenase (acetylating) activity (inferred from electronic annotation from HAMAP).
GO:0019439;	Biological process: aromatic compound catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01657; -; 1.
PBIL [Tree]

InterPro

IPR003361; Acetylald_dehydrogenase.
IPR015426; Acetylald_DHase_C.
IPR000534; Semialdehyde_DHase_NAD-bd.
Graphical view of domain structure.

PANTHER

PTHR21123; Acetylald_dh; 1.

Pfam

PF09290; AcetDehyd-dimer; 1.
PF01118; Semialdhyde_dh; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF015689; Actaldh_dh_actl; 1.

TIGRFAMs

TIGR03215; ac_ald_DH_ac; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Aromatic hydrocarbons catabolism; NAD; Oxidoreductase; Plasmid.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 312`	`312`		`Acetaldehyde dehydrogenase.`	`PRO_0000337983`

Sequence information

Length: 312 AA [This is the length of the unprocessed precursor]

Molecular weight: 32710 Da [This is the MW of the unprocessed precursor]

CRC64: 51B57FFE9CF24B43 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTTKRKVAIV GSGNVGTDLM IKILRNAEHL EMAVMVGIDP ASDGLARAGR MGVATTHEGV 

        70         80         90        100        110        120 
AGLVKMPEFA DVDFVFDATS AGAHVKNDAL LRATKPGIRV IDLTPAAIGP YCVPVVNLEQ 

       130        140        150        160        170        180 
HVNAENLNMV TCGGQATIPM VAAVSRVAKV HYAEIVASIA SKSAGPGTRA NIDEFTETTS 

       190        200        210        220        230        240 
KAIEAIGGAA KGKAIIIMNP AEPPLMMRDT VYVLSEAADQ DHVEASIEEM VAAVNAYVPG 

       250        260        270        280        290        300 
YRLKQKVQFE VIPDTAPLNI PGHGEFSGLK TSVFIEVEGA AHYLPAYAGN LDIMTSAALA 

       310 
TAERMAQSMS QA

Q49KG0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools