NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=AM1 / NCIMB 9133;
PubMed=8021187 [NCBI, ExPASy, EBI, Israel, Japan]
Chistoserdov A.Y., Chistoserdova L.V., McIntire W.S., Lidstrom M.E.;
"Genetic organization of the mau gene cluster in Methylobacterium extorquens AM1: complete nucleotide sequence and generation and characteristics of mau mutants.";
J. Bacteriol. 176:4052-4065(1994).

Comments

FUNCTION: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
CATALYTIC ACTIVITY: RCH₂NH₂ + H₂O + acceptor = RCHO + NH₃ + reduced acceptor.
SUBUNIT: Tetramer of two light and two heavy chains.
SUBCELLULAR LOCATION: Periplasm.
SIMILARITY: Belongs to the aromatic amine dehydrogenase heavy chain family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

L26406; AAB46933.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P29894; 2MTA. [HSSP ENTRY / PDB]

ModBase

Q49124.

Enzyme and pathway databases

BioCyc

MetaCyc:MON-3905; -.

Family and domain databases

InterPro

IPR013476; MeN_DHase_hvc.
IPR009451; Metamine_DHase_Hsu.
IPR015943; WD40/YVTN_repeat-like.
Graphical view of domain structure.

Gene3D

G3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1.

Pfam

PF06433; Me-amine-dh_H; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF017797; TTQ_MADH_Hv; 1.

TIGRFAMs

TIGR02658; TTQ_MADH_Hv; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Electron transport; Oxidoreductase; Periplasm; Signal; Transport.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 36`	`36`	`Potential.`
`CHAIN`	`37 411`	`375`	`Methylamine dehydrogenase heavy chain.`	`PRO_0000025577`

Sequence information

Length: 411 AA [This is the length of the unprocessed precursor]

Molecular weight: 44636 Da [This is the MW of the unprocessed precursor]

CRC64: 0899CF454A1F81B9 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MMTHAYTKVR QALCYGSATL GAAALAALIA AGSAAAAESH GVATAKAAAA DLAAGKADDP 

        70         80         90        100        110        120 
VVLKAAPINA RRVFVYDPKH FAAISQFYMI DGDTARVVGT ADGGFLSNPV VASDGSFFGQ 

       130        140        150        160        170        180 
ASTVYERIAR GKRTDYVELL DPQTNNPIAD IELPNSPRFL VGTYPWMTAL TPNNKTLLFY 

       190        200        210        220        230        240 
QFSPQPAVGV VDLAGKKFDR MIEVPDCYHI FPSSNDTFFM HCRDGSLLKV GIGADGKSQT 

       250        260        270        280        290        300 
KRTEIFHKEN EYLINHPAYS PKSGRLVWPT YTGKIFQIDL SSQDAKFLPA IEAFTDAEKK 

       310        320        330        340        350        360 
EGWAPGGWQQ VAYHRESDRI FLLGDQRAAS KHKAPSRFLF VIDAKTGKRI NKIELKHEID 

       370        380        390        400        410 
SVGVSQDAKP QLYALSTGDK ALYIFDPETG KEVSSVNQLG AGPQVVMTSD M

Q49124 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools