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UniProtKB/Swiss-Prot entry Q47XB8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HISX1_COLP3
Primary accession number Q47XB8
Secondary accession numbers None
Integrated into Swiss-Prot on January 10, 2006
Sequence was last modified on September 13, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 22)
Name and origin of the protein
Protein name Histidinol dehydrogenase 1
Synonyms HDH 1
EC 1.1.1.23
Gene name
Name: hisD1
OrderedLocusNames: CPS_3890
From
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [TaxID: 167879] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Colwelliaceae; Colwellia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0504766102; PubMed=16043709 [NCBI, ExPASy, EBI, Israel, Japan]
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses.";
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000083; AAZ27302.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_270552.1; -.
3D structure databases
ModBase Q47XB8.
Enzyme and pathway databases
BioCyc CPSY167879:CPS_3890-MON; -.
Ontologies
GO
GO:0004399; Molecular function: histidinol dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01024; -; 1.
PBIL [Tree]
InterPro IPR001692; Histidinol_DHase.
IPR012131; Hstdl_DHase_prok.
Graphical view of domain structure.
PANTHER PTHR21256:SF2; Hstdl_DH_prok; 1.
Pfam PF00815; Histidinol_dh; 1.
Pfam graphical view of domain structure.
PRINTS PR00083; HOLDHDRGNASE.
ProDom PD002680; Histidinol_dh; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00069; hisD; 1.
PROSITE PS00611; HISOL_DEHYDROGENASE; 1.
BLOCKS Q47XB8.
Genome annotation databases
GeneID 3521558; -.
GenomeReviews CP000083_GR; CPS_3890.
KEGG cps:CPS_3890; -.
NMPDR fig|167879.3.peg.3530; -.
TIGR CPS_3890; -.
Phylogenomic databases
HOGENOM Q47XB8; -.
Other
ProtoNet Q47XB8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Metal-binding; NAD; Oxidoreductase; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   434  434     Histidinol dehydrogenase 1. PRO_0000135757
ACT_SITE   329   329        Proton acceptor (By similarity). 
ACT_SITE   330   330        Proton acceptor (By similarity). 
METAL   262   262        Zinc (By similarity). 
METAL   265   265        Zinc (By similarity). 
METAL   363   363        Zinc (By similarity). 
METAL   422   422        Zinc (By similarity). 
BINDING   129   129        NAD (By similarity). 
BINDING   191   191        NAD (By similarity). 
BINDING   214   214        NAD (By similarity). 
BINDING   240   240        Substrate (By similarity). 
BINDING   262   262        Substrate (By similarity). 
BINDING   265   265        Substrate (By similarity). 
BINDING   330   330        Substrate (By similarity). 
BINDING   363   363        Substrate (By similarity). 
BINDING   417   417        Substrate (By similarity). 
BINDING   422   422        Substrate (By similarity). 
Sequence information
Length: 434 AA [This is the length of the unprocessed precursor] Molecular weight: 45853 Da [This is the MW of the unprocessed precursor] CRC64: CD2635AFC75E5169 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MINQLINWQE LSPQQKNSAL ARPAIADSAL LSTQVANILS QVKNQGDKAI LALTEQFDGI 

        70         80         90        100        110        120 
ALSTLSVSSA QVAQAKLALT DKRLKAIHTA YKQIKSFHSA QTASDITVET TPGVKCTLKT 

       130        140        150        160        170        180 
EAIESVGLYI PAGSAPLPST VLMLGVPAQL TGCQRTVLVC PPDKNGQLAD EILVAADLCG 

       190        200        210        220        230        240 
ITEIYTVGGA QAIAALAYGT ETIPAVNKVF GPGNRYVTEA KTQLSQQVAG FAIDMPAGPS 

       250        260        270        280        290        300 
EVLVIADGQA NPAFIAADLL SQAEHGVDSQ VILLSDSESL ISKVSTEIAQ QLTLLSRCKI 

       310        320        330        340        350        360 
AEQALKQSRL ILTKDLAQAV EVSNEYGPEH LIIQTEDAPT LLSKLRNAGS IFVGAYTPES 

       370        380        390        400        410        420 
AGDYASGTNH VLPTYGYSKV ISSLSLADFS RRFTVQEITK AGLQSLAECI IELTDAEGLD 

       430 
AHQRAVTIRL EEGS
Q47XB8 in FASTA format

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