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UniProtKB/Swiss-Prot entry Q42919

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_MEDSA
Primary accession number Q42919
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1998
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 51)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform
Synonyms G6PD
EC 1.1.1.49
Gene name None
From
Medicago sativa (Alfalfa) [TaxID: 3879] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids I; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Apollo;
DOI=10.1007/BF00042073; PubMed=7640360 [NCBI, ExPASy, EBI, Israel, Japan]
Fahrendorf T., Ni W., Shorrosh B.S., Dixon R.A.;
"Stress responses in alfalfa (Medicago sativa L.) XIX. Transcriptional activation of oxidative pentose phosphate pathway genes at the onset of the isoflavonoid phytoalexin response.";
Plant Mol. Biol. 28:885-900(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U18238; AAB41552.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S57785; S57785.
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase Q42919.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
BLOCKS Q42919.
Other
ProtoNet Q42919.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Cytoplasm; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   515  515     Glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform. PRO_0000068100
ACT_SITE   274   274        Proton acceptor (By similarity). 
BINDING   38    38        NADP (By similarity). 
BINDING   71    71        NADP (By similarity). 
BINDING   212   212        Substrate (By similarity). 
BINDING   216   216        Substrate (By similarity). 
Sequence information
Length: 515 AA [This is the length of the unprocessed precursor] Molecular weight: 58923 Da [This is the MW of the unprocessed precursor] CRC64: 836C1B96F2709FC7 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MGTNEWHVER RDSIGTESPV AREVLETGTL SIVVLGASGD LAKKKTFPAL FHLYKQELLP 

        70         80         90        100        110        120 
PDEVHIFGYA RSKISDDELR NKLRSYLVPE KGASPKQLDD VSKFLQLVKY VSGPYDSEDG 

       130        140        150        160        170        180 
FRLLDKEISE HEYLKNSKEG SSRRLFYLAL PPSVYPSVCK MIKTCCMNKS DLGGWTRVVV 

       190        200        210        220        230        240 
EKPFGRDLES AEELSTQIGE LFEEPQIYRI DHYLGKELVQ NMLVLRFANR FFLPLWNHNH 

       250        260        270        280        290        300 
IDNVQIVFRE DFGTDGRGGY FDQYGIIRDI IPNHLLQVLC LIAMEKPVSL KPEHIRDEKV 

       310        320        330        340        350        360 
KVLESVLPIR DDEVVLGQYE GYTDDPTVPD DSNTPTFATT ILRIHNERWE GVPFIVKAGK 

       370        380        390        400        410        420 
ALNSRKAEIR VQFKDVPGDI FRSKKQGRNE FVIRLQPSEA IYMKLTVKQP GLEMSAVQSE 

       430        440        450        460        470        480 
LDLSYGQRYQ GITIPEAYER LILDTIRGDQ QHFVRRDELK ASWQIFTPLL HKIDRGELKP 

       490        500        510 
VPYNPGSRGP AEADELLEKA GYVQTPGYIW IPPTL
Q42919 in FASTA format

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