[1]	NUCLEOTIDE SEQUENCE [MRNA]. DOI=10.1007/BF00020185; PubMed=7888620 [NCBI, ExPASy, EBI, Israel, Japan] Ishitani M., Nakamura T., Han S.Y., Takabe T.; "Expression of the betaine aldehyde dehydrogenase gene in barley in response to osmotic stress and abscisic acid."; Plant Mol. Biol. 27:307-315(1995).

Comments

CATALYTIC ACTIVITY: Betaine aldehyde + NAD⁺ + H₂O = betaine + NADH.
PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1 .
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Peroxisome (Potential).
SIMILARITY: Belongs to the aldehyde dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

D26448; BAA05466.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S71413; S71413.

UniGene

Hv.61

3D structure databases

HSSP

P05091; 1O04. [HSSP ENTRY / PDB]

ModBase

Q40024.

Organism-specific databases

Gramene

Q40024; -.

Family and domain databases

InterPro

IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.

PANTHER

PTHR11699; Aldehyde_dehyd; 1.

Pfam

PF00171; Aldedh; 1.
Pfam graphical view of domain structure.

PROSITE

PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NAD; Oxidoreductase; Peroxisome.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 505`	`505`	`Betaine aldehyde dehydrogenase.`	`PRO_0000056529`
`NP_BIND`	`239 244`	`6`	`NAD (By similarity).`
`MOTIF`	`503 505`	`3`	`Microbody targeting signal (Potential).`
`ACT_SITE`	`261 261`		`Proton acceptor (By similarity).`
`ACT_SITE`	`296 296`		`Nucleophile (By similarity).`
`SITE`	`163 163`	`1`	`Transition state stabilizer (By similarity).`

Sequence information

Length: 505 AA [This is the length of the unprocessed precursor]

Molecular weight: 54290 Da [This is the MW of the unprocessed precursor]

CRC64: C30B40FF22413BB6 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAAPPAIPRR GLFIGGGWRE PTLGRHIPVI NPATEDTIGD IPAATAEDVE LAVAAGGPVL 

        70         80         90        100        110        120 
ARRREPWARA SGATRAKYLN AIAAKITGKI AYLALLETVD SGKPKDEAVA DMDDVAACFE 

       130        140        150        160        170        180 
YYAALAEALD GKQHAPISLP MEEFKTYVLK EPIGVVGLIT PWNYPLLMAT WKVAPALAAG 

       190        200        210        220        230        240 
CTAVLKPSEL ASLTCLELGA ICEEIGLPSG VLNIITGLGP DAGAPIASHP HVDKIAFTGS 

       250        260        270        280        290        300 
TATGKTIMTA AAQMVKPVSL ELGGKSPLVT FDDVADIDKA VEWPMLGCFF NGGQVCSATS 

       310        320        330        340        350        360 
RLLLHEKIAE PFLDRLVEWA KNIKISDPLE EGCRLGSVIS KGQYEQIKKF ISTARSEGAT 

       370        380        390        400        410        420 
ILHGGDRPKH LGKGFFIEPT INTGVSTSMQ IWREEVFGPV ICVKVFKTES EAVELANDTH 

       430        440        450        460        470        480 
YGLAGGVISD DLERCERIAK VIHSGIVWKN CSQPTLVQAP WGGNKRSGFG RELGEWGLEN 

       490        500 
YLSVKQVTRY CKDELYGWYQ RPSKL

Q40024 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools