NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyripides N., Anderson I., Richardson P.;
"Complete sequence of Pseudomonas fluorescens PfO-1.";
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity).
CATALYTIC ACTIVITY: N²-succinyl-L-arginine + 2 H₂O = N²-succinyl-L-ornithine + 2 NH₃ + CO₂.
PATHWAY: Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5 .
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the succinylarginine dihydrolase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000094; ABA76018.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_350009.1; -.

3D structure databases

ModBase

Q3K886.

Enzyme and pathway databases

BioCyc

PFLU205922:PFL_4281-MON; -.

Ontologies

GO:0009015;	Molecular function: N-succinylarginine dihydrolase activity (inferred from electronic annotation from HAMAP).
GO:0019544;	Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01172; -; 1.
PBIL [Tree]

InterPro

IPR007079; SuccinylArg_d-OHase_AstB.
Graphical view of domain structure.

Gene3D

G3DSA:3.75.10.20; SuccinylArg_di_hydro; 1.

Pfam

PF04996; AstB; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR03241; arg_catab_astB; 1.

Genome annotation databases

GeneID

3712893; -.

GenomeReviews

CP000094_GR; PflO1_4281.

KEGG

pfo:PflO1_4281; -.

Phylogenomic databases

HOGENOM

Q3K886; -.

Genome annotation databases

CMR

Q3K886; Pfl01_4281.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Arginine metabolism; Complete proteome; Hydrolase.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 448`	`448`	`N-succinylarginine dihydrolase.`	`PRO_0000262366`
`REGION`	`19 28`	`10`	`Substrate binding (By similarity).`
`REGION`	`137 138`	`2`	`Substrate binding (By similarity).`
`ACT_SITE`	`174 174`		`By similarity.`
`ACT_SITE`	`250 250`		`By similarity.`
`ACT_SITE`	`371 371`		`Nucleophile (By similarity).`
`BINDING`	`110 110`		`Substrate (By similarity).`
`BINDING`	`214 214`		`Substrate (By similarity).`
`BINDING`	`252 252`		`Substrate (By similarity).`
`BINDING`	`365 365`		`Substrate (By similarity).`

Sequence information

Length: 448 AA [This is the length of the unprocessed precursor]

Molecular weight: 48728 Da [This is the MW of the unprocessed precursor]

CRC64: 66F70560E487848A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKSYEVNFDG LVGPTHNYGG LSYGNVASQS NSQQSSNPKE AALQGLAKMK ALMEMGFQQG 

        70         80         90        100        110        120 
VLAPQERPDV AALRRLGFSG TDAQVIERAA KEAMPLLVAS CSASSMWVAN AATVSPSADT 

       130        140        150        160        170        180 
ADGRVHFTAA NLNCKYHRSI EHPTTSRVLG AMFANQQHFA HHAALPAVAQ FGDEGAANHT 

       190        200        210        220        230        240 
RFCREYGDAG VEFFVFGRSA FDTRYPAPQK YPARQTLEAS QAVARLHGLR DDGVVYAQQN 

       250        260        270        280        290        300 
PAVIDQGVFH NDVIAVGNGE VLFYHEDAFL DTDQMLAELQ AKLAKVGGKF QSVCVPRSAV 

       310        320        330        340        350        360 
TVDDAVRSYL FNSQLLSRPD GSMLLIVPEE CRGNERVWNY LQGLTSSGGL IREVKVFDLK 

       370        380        390        400        410        420 
QSMQNGGGPA CLRLRVALNE TELAAVNPGV IMTAPLYGSL TAWVEKHYRD RLTESDLADP 

       430        440 
QLLLECRTAL DELTQILKLG AVYPFQIN

Q3K886 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools