ID   BETB_XANC5              Reviewed;         490 AA.
AC   Q3BXK7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   04-NOV-2008, entry version 22.
DE   RecName: Full=Betaine aldehyde dehydrogenase;
DE            Short=BADH;
DE            EC=1.2.1.8;
GN   Name=betB; OrderedLocusNames=XCV0775;
OS   Xanthomonas campestris pv. vesicatoria (strain 85-10).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xanthomonas.
OX   NCBI_TaxID=316273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16237009; DOI=10.1128/JB.187.21.7254-7266.2005;
RA   Thieme F., Koebnik R., Bekel T., Berger C., Boch J., Buettner D.,
RA   Caldana C., Gaigalat L., Goesmann A., Kay S., Kirchner O., Lanz C.,
RA   Linke B., McHardy A.C., Meyer F., Mittenhuber G., Nies D.H.,
RA   Niesbach-Kloesgen U., Patschkowski T., Rueckert C., Rupp O.,
RA   Schneiker S., Schuster S.C., Vorhoelter F.J., Weber E., Puehler A.,
RA   Bonas U., Bartels D., Kaiser O.;
RT   "Insights into genome plasticity and pathogenicity of the plant
RT   pathogenic Bacterium Xanthomonas campestris pv. vesicatoria revealed
RT   by the complete genome sequence.";
RL   J. Bacteriol. 187:7254-7266(2005).
CC   -!- CATALYTIC ACTIVITY: Betaine aldehyde + NAD(+) + H(2)O = betaine +
CC       NADH.
CC   -!- PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis
CC       via choline pathway; betaine from betaine aldehyde: step 1/1.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; AM039952; CAJ22406.1; -; Genomic_DNA.
DR   RefSeq; YP_362506.1; -.
DR   GeneID; 3729800; -.
DR   GenomeReviews; AM039952_GR; XCV0775.
DR   KEGG; xcv:XCV0775; -.
DR   NMPDR; fig|316273.3.peg.1263; -.
DR   HOGENOM; Q3BXK7; -.
DR   BioCyc; XCAM316273:XCV0775-MON; -.
DR   GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0019285; P:glycine betaine biosynthetic process from c...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00804; -; 1.
DR   InterPro; IPR016160; Ald_DHase_CS.
DR   InterPro; IPR016162; Ald_DHase_N.
DR   InterPro; IPR015590; Aldehyde_DHase.
DR   InterPro; IPR011264; Betaine_Ald_DHase.
DR   Gene3D; G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   TIGRFAMs; TIGR01804; BADH; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    490       Betaine aldehyde dehydrogenase.
FT                                /FTId=PRO_1000047060.
FT   NP_BIND     229    234       NAD (By similarity).
FT   ACT_SITE    252    252       By similarity.
FT   ACT_SITE    286    286       By similarity.
SQ   SEQUENCE   490 AA;  52392 MW;  B86DD85BC53A38ED CRC64;
     MPRFSDQLLY IGGRYVPARG GHTFEVVNPA TGEVLANVHN AGADDLDAAV DSAQAGQRQW
     AALTTVERSR ILLRAVALLR ERNDALAELE TLNTGKPLSE TRSVDVVTGA DVLEYYAGVA
     QALQGAQVPL REGSFFYTRH EPLGVVGAIG AWNYPIQIAL WKAAPALAAG NAMIFKPSEV
     TPLTALKLAE IFTEAGLPDG VFNVLPGDGA SVGTALTEHP QIEKISFTGG TATGRKVMAS
     ASSSSLKEVT MELGGKSPLI VCADADLDLA ADIAMMANFY SSGQVCTNGT RVFVPRALRH
     AFEARLLARV QRIHIGDPLD ERTTFGPLVS AAHMQRVLEH IEQGKAEGAR LLCGGERLQD
     GALAQGYYVA PTIFSDCTDV MTIVREEIFG PVLSLLTYDD EDEAVTRANA TTYGLAAGVV
     TPDLARAHRL IHRLEAGICW VNTWGESPAP MPVGGYKQSG VGRENGLATL QAYTRTKSVQ
     IELERYASVF
//