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UniProtKB/Swiss-Prot entry Q3AR25

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HISX_CHLCH
Primary accession number Q3AR25
Secondary accession numbers None
Integrated into Swiss-Prot on April 4, 2006
Sequence was last modified on November 22, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 21)
Name and origin of the protein
Protein name Histidinol dehydrogenase
Synonyms HDH
EC 1.1.1.23
Gene name
Name: hisD
OrderedLocusNames: Cag_1289
From
Chlorobium chlorochromatii (strain CaD3) [TaxID: 340177] [HAMAP proteome]
Taxonomy Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobium/Pelodictyon group; Chlorobium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
"Complete sequence of Chlorobium chlorochromatii CaD3.";
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000108; ABB28550.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_379593.1; -.
3D structure databases
ModBase Q3AR25.
Enzyme and pathway databases
BioCyc CCHL340177:CAG_1289-MON; -.
Ontologies
GO
GO:0004399; Molecular function: histidinol dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0000105; Biological process: histidine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01024; -; 1.
PBIL [Tree]
InterPro IPR001692; Histidinol_DHase.
IPR012131; Hstdl_DHase_prok.
Graphical view of domain structure.
PANTHER PTHR21256:SF2; Hstdl_DH_prok; 1.
Pfam PF00815; Histidinol_dh; 1.
Pfam graphical view of domain structure.
PRINTS PR00083; HOLDHDRGNASE.
ProDom PD002680; Histidinol_dh; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00069; hisD; 1.
PROSITE PS00611; HISOL_DEHYDROGENASE; 1.
BLOCKS Q3AR25.
Genome annotation databases
GeneID 3747438; -.
GenomeReviews CP000108_GR; Cag_1289.
KEGG cch:Cag_1289; -.
Phylogenomic databases
HOGENOM Q3AR25; -.
Genome annotation databases
CMR Q3AR25; Cag_1289.
Other
ProtoNet Q3AR25.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Metal-binding; NAD; Oxidoreductase; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   428  428     Histidinol dehydrogenase. PRO_0000229855
ACT_SITE   324   324        Proton acceptor (By similarity). 
ACT_SITE   325   325        Proton acceptor (By similarity). 
METAL   256   256        Zinc (By similarity). 
METAL   259   259        Zinc (By similarity). 
METAL   358   358        Zinc (By similarity). 
METAL   417   417        Zinc (By similarity). 
BINDING   126   126        NAD (By similarity). 
BINDING   188   188        NAD (By similarity). 
BINDING   211   211        NAD (By similarity). 
BINDING   234   234        Substrate (By similarity). 
BINDING   256   256        Substrate (By similarity). 
BINDING   259   259        Substrate (By similarity). 
BINDING   325   325        Substrate (By similarity). 
BINDING   358   358        Substrate (By similarity). 
BINDING   412   412        Substrate (By similarity). 
BINDING   417   417        Substrate (By similarity). 
Sequence information
Length: 428 AA [This is the length of the unprocessed precursor] Molecular weight: 46058 Da [This is the MW of the unprocessed precursor] CRC64: 9C84F276D42A901E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLPLYRFPQE ASALQERLVR HVSFDEAAHK AVDEILAKVR QQGDRAVLNY TEQFQGVRLT 

        70         80         90        100        110        120 
SMQVDEEAIE MAYRHADPSL IATLHEAYAN IVRFHEHEVE RSFFYEAEGG VLLGQRVRPM 

       130        140        150        160        170        180 
ERAMLYVPGG KAAYPSSLLM NAAPAKVAGV CEIAVTTPCD ATGVVNPTIL AAAKVAGISS 

       190        200        210        220        230        240 
IYKIGGAQAV AAFAYGTESI PKVDIITGPG NKYVALAKKQ VFGHVAIDSI AGPSEVVIIA 

       250        260        270        280        290        300 
DESAHAEFVA LDMFAQAEHD PDASAVLITT SESFAQAVQQ AVASLLPTML RHETIASSLL 

       310        320        330        340        350        360 
HNGAMVLVPS LDDACAVSDM LAPEHLELHV VQPWDILPKL KHAGAIFMGS YSCETIGDYF 

       370        380        390        400        410        420 
AGPNHTLPTS GTARFFSPLS VRDFVKHTSI ISYSPEQLRS KGAQIAAFAD AEGLQAHAEA 


VRVRLKTL
Q3AR25 in FASTA format

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