NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
"Complete sequence of Chlorobium chlorochromatii CaD3.";
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Shikimate + NADP⁺ = 3-dehydroshikimate + NADPH.
PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and PEP: step 4/7 .
SIMILARITY: Belongs to the shikimate dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000108; ABB28605.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_379648.1; -.

3D structure databases

ModBase

Q3AQX0.

Enzyme and pathway databases

BioCyc

CCHL340177:CAG_1345-MON; -.

Ontologies

GO:0004764;	Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073;	Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

HAMAP

MF_00222; -; 1.
PBIL [Tree]

InterPro

IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.

Pfam

PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.

TIGR00507; aroE; 1.

Genome annotation databases

GeneID

3746860; -.

GenomeReviews

CP000108_GR; Cag_1345.

KEGG

cch:Cag_1345; -.

Phylogenomic databases

HOGENOM

Q3AQX0; -.

Genome annotation databases

CMR

Q3AQX0; Cag_1345.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 287`	`287`	`Shikimate dehydrogenase.`	`PRO_1000021270`
`NP_BIND`	`130 134`	`5`	`NADP (By similarity).`
`ACT_SITE`	`70 70`		`Proton acceptor (Potential).`

Sequence information

Length: 287 AA [This is the length of the unprocessed precursor]

Molecular weight: 31219 Da [This is the MW of the unprocessed precursor]

CRC64: B6940A63C3CEB9B7 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNSSTRIFAL LGRAVDYSYS PLIHNTAFQA LGLPYHYTIF NIAEAALVGD ALRGARALGL 

        70         80         90        100        110        120 
GGFSVTIPYK QTVVPFLDEL SEEATTIQAV NCIVNKNGKL IGYNTDILGF ASPLFAYREA 

       130        140        150        160        170        180 
LHGATIALFG SGGAALAAIE AFQRYFTPKQ VLLFARDSQK AKSQLRSSLA LERYTNLAIV 

       190        200        210        220        230        240 
PLSDYERVRE CRLVINATPL GTKGRADGSA IIPLESNLLH SEHIVYDMVY NPTITPLLQA 

       250        260        270        280 
AQAVGASTIF GIEMLIGQAE QAFTLWTGEK MPTELVRQTV MAKLQEL

Q3AQX0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools