NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=263-11;
DOI=10.1006/jmbi.1994.1210; PubMed=8133522 [NCBI, ExPASy, EBI, Israel, Japan]
Wolff G., Plante I., Lang B.F., Kueck U., Burger G.;
"Complete sequence of the mitochondrial DNA of the chlorophyte alga Prototheca wickerhamii. Gene content and genome organization.";
J. Mol. Biol. 237:75-86(1994).

Comments

FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
CATALYTIC ACTIVITY: NADH + ubiquinone = NAD⁺ + ubiquinol.
CATALYTIC ACTIVITY: NADH + acceptor = NAD⁺ + reduced acceptor.
SUBUNIT: Complex I is composed of about 30 different subunits.
SUBCELLULAR LOCATION: Mitochondrion inner membrane (By similarity). Note=Matrix and cytoplasmic side of the mitochondrial inner membrane (By similarity).
SIMILARITY: Belongs to the complex I 30 kDa subunit family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U02970; AAD12649.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

T11930; T11930.

RefSeq

NP_042261.1; -.

3D structure databases

ModBase

Q37622.

Family and domain databases

InterPro

IPR010218; NADH_DH_csu.
IPR001268; NADH_DHase_Ub_30kDa_su.
Graphical view of domain structure.

Pfam

PF00329; Complex1_30kDa; 1.
Pfam graphical view of domain structure.

ProDom

PD001581; Complex1_30K; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGRFAMs

TIGR01961; NuoC_fam; 1.

PROSITE

PS00542; COMPLEX1_30K; 1.

BLOCKS

Q37622.

Genome annotation databases

GeneID

802143; -.

Other

ProtoNet

Q37622.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain; Transport; Ubiquinone.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 192`	`192`		`NADH-ubiquinone oxidoreductase subunit 9.`	`PRO_0000118648`

Sequence information

Length: 192 AA [This is the length of the unprocessed precursor]

Molecular weight: 23204 Da [This is the MW of the unprocessed precursor]

CRC64: F04204944207582D [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNNNFEKSIL LMVPQWIQYH VSHRNETTFY VYPEYLKPFL YFLRDHMSTQ YKVCIDITAA 

        70         80         90        100        110        120 
DYPSRASRFE CVYNLLSVEY NSRIRIKTCV DEITTLESVT PVYSSAAWWE REVWDMFGVF 

       130        140        150        160        170        180 
FHNHPDLRRI LTDYGFQGHP LRKDFPLSGY VEVRYDDSEK RVCIESVEYS QEFRYFDFES 

       190 
PWEQVDKNSL LK

Q37622 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools