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- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme.
- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD+ + ubiquinol.
- CATALYTIC ACTIVITY: NADH + acceptor = NAD+ + reduced acceptor.
- SUBCELLULAR LOCATION: Mitochondrion.
- SIMILARITY: Belongs to the complex I 49 kDa subunit family.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 401 AA [This is the length of the unprocessed precursor] |
Molecular weight: 46096 Da [This is the MW of the unprocessed precursor] |
CRC64: BA929F88024C0DF8 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MRKNQISPYI KTSKIKNFTM NFGPQHPAAH GVLRLILELD GELVRKADPH IGLLHRGTEK
70 80 90 100 110 120
LIEYKTYIQA LPYFDRLDYV SMMSQEHAYS LAIEKLLNCN VPIRAQYIRV IYSELTRILN
130 140 150 160 170 180
HILAVTTHAM DVGALTPFLW LFEEREKLME FYERVSGARM HAAYIRPGGV AQDFPLGLWN
190 200 210 220 230 240
DIMQFVEQFF WRLVEVEELL NGNRIWKQRL VDVGIVTAEE ALSHGFSGVM LRGSGIAWDL
250 260 270 280 290 300
RKNNPYEVYN KLNFNIPIGK NGDCYDRYLI RVYEMYESLN IIKQCLTAMP AGLIKVNDKK
310 320 330 340 350 360
ITPPERTDMK YSMESLIHHF KLYSEGFNVP ENETYACVEA PKGEFGVYVV SDGSNKPYRC
370 380 390 400
KIKAPGFLHL QSLNSMSKGH MIADVVTIIG TQDIVFGEID R
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Q37384 in FASTA format |
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