NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.;
"Complete sequence of Prochlorococcus marinus str. MIT 9312.";
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity).
CATALYTIC ACTIVITY: ATP + NAD⁺ = ADP + NADP⁺.
COFACTOR: Divalent metal ions (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the NAD kinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000111; ABB49220.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_396656.1; -.

3D structure databases

ModBase

Q31D25.

Enzyme and pathway databases

BioCyc

PMAR74546:PMT9312_0158-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0046872;	Molecular function: metal ion binding (inferred from electronic annotation from HAMAP).
GO:0003951;	Molecular function: NAD+ kinase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00361; -; 1.
PBIL [Tree]

InterPro

IPR017438; ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504; ATP_NADK.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.200.30; ATP-NAD_kinase_PpnK-typ; 1.
G3DSA:3.40.50.10330; ATP-NAD_kinase_PpnK-typ_a/b; 1.

PANTHER

PTHR20275; ATP_NADK; 1.

Pfam

PF01513; NAD_kinase; 1.
Pfam graphical view of domain structure.

Genome annotation databases

GeneID

3764943; -.

GenomeReviews

CP000111_GR; PMT9312_0158.

KEGG

pmi:PMT9312_0158; -.

Phylogenomic databases

HOGENOM

Q31D25; -.

Genome annotation databases

CMR

Q31D25; PMT9312_0158.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Kinase; NAD; NADP; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 303`	`303`		`Probable inorganic polyphosphate/ATP-NAD kinase 1.`	`PRO_0000229668`

Sequence information

Length: 303 AA [This is the length of the unprocessed precursor]

Molecular weight: 34065 Da [This is the MW of the unprocessed precursor]

CRC64: 14B8B84A93AD5792 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKLSLVLIIY RSDSSIALEA SKFCEEVLKA KNIKSNRIAS DFHRDEIEKN LYNTKFQPDI 

        70         80         90        100        110        120 
GIVLGGDGTF LKCANALADY DIPLLSINIG GNLGFLTQEK DFLFDKSFIE ILENEEYIID 

       130        140        150        160        170        180 
SRNRLNCNVC ISERSPEKKI IKSYDALNDF YFKSVEEAIS PTNQIQIEID NEKVNEYKGD 

       190        200        210        220        230        240 
GLIISTSTGS TAYSMAAGGP IVHPSIDAMI INPICPMSLA SRPIVIPNTS KVIIKPVKKS 

       250        260        270        280        290        300 
KGEIKLWRDG SKCMTIKETY YCEIKKGKAP CKIIKFKKST NYYNTLIKKL DWKGDLSLKN 


SKN

Q31D25 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools