[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. DOI=10.1371/journal.pone.0001120; PubMed=17971880 [NCBI, ExPASy, EBI, Israel, Japan] Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.; "Molecular correlates of host specialization in Staphylococcus aureus."; PLoS ONE 2:E1120-E1120(2007).

Comments

CATALYTIC ACTIVITY: An aldehyde + NAD⁺ + H₂O = an acid + NADH.
SIMILARITY: Belongs to the aldehyde dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ938182; CAI81695.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_417464.1; -.

3D structure databases

ModBase

Q2YUN1.

Enzyme and pathway databases

BioCyc

SAUR273036:SAB2006C-MON; -.

Ontologies

GO:0004029;	Molecular function: aldehyde dehydrogenase (NAD) activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

InterPro

IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.

PANTHER

PTHR11699; Aldehyde_dehyd; 1.

Pfam

PF00171; Aldedh; 1.
Pfam graphical view of domain structure.

PROSITE

PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.

BLOCKS

Q2YUN1.

Genome annotation databases

GeneID

3792832; -.

GenomeReviews

AJ938182_GR; SAB2006c.

KEGG

sab:SAB2006c; -.

NMPDR

fig|273036.3.peg.1945; -.

Phylogenomic databases

HOGENOM

Q2YUN1; -.

Genome annotation databases

CMR

Q2YUN1; SAB2006c.

Other

ProtoNet

Q2YUN1.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 475`	`475`	`Putative aldehyde dehydrogenase SAB2006c.`	`PRO_0000293552`
`NP_BIND`	`201 207`	`7`	`NAD (By similarity).`
`ACT_SITE`	`245 245`		`By similarity.`
`ACT_SITE`	`279 279`		`By similarity.`

Sequence information

Length: 475 AA [This is the length of the unprocessed precursor]

Molecular weight: 51988 Da [This is the MW of the unprocessed precursor]

CRC64: DD2112D65C182F2D [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRDYTKQYIN GEWVESNSNE TIEVINPATE EVIGKVAKGN KADVDKAVEA ADNAYLEFRH 

        70         80         90        100        110        120 
TSVKERQALL DKIVKEYENR KDDIVQAITD ELGAPLSLSE RVHYQMGLNH FVAARDALDN 

       130        140        150        160        170        180 
YEFEERRGDD LVVKEAIGVS GLITPWNFPT NQTSLKLAAA FATGSPVVLK PSEETPFAAV 

       190        200        210        220        230        240 
ILAEIFDKVG VPKGVFNLVN GDGAGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK 

       250        260        270        280        290        300 
KVSLELGGKS PYIVLDDVDI KEAAKATTGK VVNNTGQVCT AGTRVLVPNK IKDAFLAELK 

       310        320        330        340        350        360 
EQFSQVRVGN PREDGTQVGP MISKKQFDQV QNYINKGIEE GAELFYGGPG KPEGLEKGYF 

       370        380        390        400        410        420 
ARPTIFINVD NQMTIAQEEI FGPVMSVITY NDLDEAIQIA NDTKYGLAGY VIGKDKETLH 

       430        440        450        460        470 
KVARSIEAGT VEINEAGRKP DLPFGGYKQS GLGREWGDYG IEEFLEVKSI AGYFK

Q2YUN1 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools