[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Nipponbare; DOI=10.1186/1741-7007-3-20; PubMed=16188032 [NCBI, ExPASy, EBI, Israel, Japan] The rice chromosomes 11 and 12 sequencing consortia; "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."; BMC Biol. 3:20-20(2005).
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Nipponbare; DOI=10.1038/nature03895; PubMed=16100779 [NCBI, ExPASy, EBI, Israel, Japan] International rice genome sequencing project (IRGSP); "The map-based sequence of the rice genome."; Nature 436:793-800(2005).
[3]	GENOME REANNOTATION. STRAIN=cv. Nipponbare; DOI=10.1101/gr.5509507; PubMed=17210932 [NCBI, ExPASy, EBI, Israel, Japan] The rice annotation project (RAP); "Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana."; Genome Res. 17:175-183(2007).

Comments

FUNCTION: Lignin degradation and detoxification of lignin-derived products (By similarity).
CATALYTIC ACTIVITY: 4 benzenediol + O₂ = 4 benzosemiquinone + 2 H₂O.
COFACTOR: Binds 4 copper ions per monomer (By similarity).
SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast (Potential).
SIMILARITY: Belongs to the multicopper oxidase family.
SIMILARITY: Contains 3 plastocyanin-like domains.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

DP000011; ABA96185.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AP008218; BAF28967.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_001065948.1; -.

UniGene

Os.56166

3D structure databases

ModBase

Q2QYS3.

Organism-specific databases

Gramene

Q2QYS3; -.

Family and domain databases

InterPro

IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
IPR017761; Laccase.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.40.420; Cupredoxin; 3.

Pfam

PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.

PROSITE

PS00079; MULTICOPPER_OXIDASE1; 1.
PS00080; MULTICOPPER_OXIDASE2; 1.

BLOCKS

Q2QYS3.

Genome annotation databases

GeneID

4351276; -.

KEGG

osa:4351276; -.

Other

ProtoNet

Q2QYS3.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Apoplast; Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 22`	`22`	`Potential.`
`CHAIN`	`23 567`	`545`	`Laccase-23.`	`PRO_0000291910`
`DOMAIN`	`30 146`	`117`	`Plastocyanin-like 1.`
`DOMAIN`	`158 310`	`153`	`Plastocyanin-like 2.`
`DOMAIN`	`415 551`	`137`	`Plastocyanin-like 3.`
`METAL`	`80 80`		`Copper 1 (By similarity).`
`METAL`	`82 82`		`Copper 2 (By similarity).`
`METAL`	`125 125`		`Copper 2 (By similarity).`
`METAL`	`127 127`		`Copper 3 (By similarity).`
`METAL`	`468 468`		`Copper 4 (By similarity).`
`METAL`	`471 471`		`Copper 1 (By similarity).`
`METAL`	`473 473`		`Copper 3 (By similarity).`
`METAL`	`530 530`		`Copper 3 (By similarity).`
`METAL`	`531 531`		`Copper 4 (By similarity).`
`METAL`	`532 532`		`Copper 2 (By similarity).`
`METAL`	`536 536`		`Copper 4 (By similarity).`
`CARBOHYD`	`76 76`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`187 187`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`241 241`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`298 298`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`312 312`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`327 327`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`365 365`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`368 368`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`378 378`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`388 388`		`N-linked (GlcNAc...) (Potential).`
`CARBOHYD`	`430 430`		`N-linked (GlcNAc...) (Potential).`

Sequence information

Length: 567 AA [This is the length of the unprocessed precursor]

Molecular weight: 61565 Da [This is the MW of the unprocessed precursor]

CRC64: 2507A6CBDAE29D74 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MGSRGCSCWL LSLALLCSLA AAKEQYHEFV IRETTVKRLC KSQSIMTVNG QFPGPTLEIK 

        70         80         90        100        110        120 
EGDSLIINLI NRGRYNVTLH WHGVRQMRTG WSDGPEYVTQ CPVRPGQSYR YRFTVAAQEG 

       130        140        150        160        170        180 
TLWWHAHSSW LRATVYGALL IRPRDGTSYP FHVQPTRELA PILLGEWWDM NPVDVVRAAT 

       190        200        210        220        230        240 
RTGAAPNISD ALTVNAQPGD LYSCSSHDTA FFPVTSGETN LLRFINAALN TELFVSLAGH 

       250        260        270        280        290        300 
NMTVVAADAS YTKPYTTSLL LLAPGQTTDV LVTFDQPPGR YYLAARAYAS AQGVPFDNTT 

       310        320        330        340        350        360 
TTAIFDYGAA NNASSAAIAM PTLPAYNDTT AATAFTTNLR GLRKAELPSR VDESLFFTVG 

       370        380        390        400        410        420 
VGLFNCTNAT AQQCGGPNGT RFAASINNVS FVLPSSTSIL QAHHHGAPGG VFTADFPASP 

       430        440        450        460        470        480 
PVQFDYTAQN VSRALWQPVP GTKVYKLKYG SAVQVVLQGT NIFAGENHPI HLHGYDFYIL 

       490        500        510        520        530        540 
AEGLGNFDAG ADTAKFNMED PPMRNTVGVP VNGWAVIRFV ADNPGVWLMH CHLDVHITWG 

       550        560 
LAMAFLVDDG VGELQSLEAP PPDLPLC

Q2QYS3 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools