[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Ochiai H., Inoue Y., Takeya M., Sasaki A., Kaku H.; "Genome sequence of Xanthomonas oryzae pv. oryzae suggests contribution of large numbers of effector genes and insertion sequences to its race diversity."; Jpn. Agric. Res. Q. 39:275-287(2005).

Comments

FUNCTION: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ (By similarity).
CATALYTIC ACTIVITY: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O₂ = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H₂O₂ + 2 H₂O.
PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis .
SIMILARITY: Belongs to the pqqC family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP008229; BAE68390.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_450664.1; -.

3D structure databases

ModBase

Q2P4Y7.

Enzyme and pathway databases

BioCyc

XORY342109:XOO1635-MON; -.

Ontologies

GO:0018189;	Biological process: pyrroloquinoline quinone biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00654; -; 1.
PBIL [Tree]

InterPro

IPR016084; Haem_Oase-like_multi-hlx.
IPR011845; PQQ_synth_PqqC.
IPR004305; TENA/THI4/PQQ_synth_PqqC.
Graphical view of domain structure.

Gene3D

G3DSA:1.20.910.10; Haem_Oase-like_multi-hlx; 1.

Pfam

PF03070; TENA_THI-4; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR02111; PQQ_syn_pqqC; 1.

BLOCKS

Q2P4Y7.

Genome annotation databases

GeneID

3860021; -.

GenomeReviews

AP008229_GR; XOO1635.

KEGG

xom:XOO_1635; -.

Phylogenomic databases

HOGENOM

Q2P4Y7; -.

Genome annotation databases

CMR

Q2P4Y7; XOO1635.

Other

ProtoNet

Q2P4Y7.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Oxidoreductase; PQQ biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 250`	`250`		`Pyrroloquinoline-quinone synthase.`	`PRO_1000061682`

Sequence information

Length: 250 AA [This is the length of the unprocessed precursor]

Molecular weight: 28027 Da [This is the MW of the unprocessed precursor]

CRC64: 46C8E4310C928633 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSALLSPDQL EADLRAIGAR LYHDQHPFHA LLHHGKLDRG QVQAWALNRF EYQRCIPLKD 

        70         80         90        100        110        120 
AAILARMEDP TLRRIWRQRI VDHDGNSATD GGIARWLHLT DALGLDRTLV ESGRALLPGT 

       130        140        150        160        170        180 
RFAVQAYLQF VSEKSLLEAI ASSLTELFAP NIIGQRVAGM LKHYDFVSSD ALAYFEHRLT 

       190        200        210        220        230        240 
EAPRDSDFAL DYVKQHADTV EKQALVKAAL HFKCSVLWAQ LDALHVAYVT PGIVWPDAFV 

       250 
PDRDASRVAA

Q2P4Y7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools