[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Gloeckner G., Schaap P., Winckler T.; "Evolutionary trends found in social amoebae."; Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
CATALYTIC ACTIVITY: NADH + ubiquinone = NAD⁺ + ubiquinol.
CATALYTIC ACTIVITY: NADH + acceptor = NAD⁺ + reduced acceptor.
SUBUNIT: Complex I is composed of about 30 different subunits.
SUBCELLULAR LOCATION: Mitochondrion inner membrane (By similarity).
SIMILARITY: Belongs to the complex I 30 kDa subunit family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

DQ336395; ABC60379.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_492628.1; -.

3D structure databases

ModBase

Q2LCR4.

Family and domain databases

InterPro

IPR001268; NADH_DHase_Ub_30kDa_su.
Graphical view of domain structure.

Pfam

PF00329; Complex1_30kDa; 1.
Pfam graphical view of domain structure.

ProDom

PD001581; Complex1_30K; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00542; COMPLEX1_30K; 1.

BLOCKS

Q2LCR4.

Genome annotation databases

GeneID

3912610; -.

Other

ProtoNet

Q2LCR4.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain; Transport; Ubiquinone.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 209`	`209`		`NADH-ubiquinone oxidoreductase subunit 9.`	`PRO_0000312397`

Sequence information

Length: 209 AA [This is the length of the unprocessed precursor]

Molecular weight: 24881 Da [This is the MW of the unprocessed precursor]

CRC64: 0C609399DD0D0484 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKDYKNELKV KVDLGENLRG SIPGLIKKVM YKTQYLEIQV EKKNLLPVLR FLKESSKYQC 

        70         80         90        100        110        120 
TMLLDIVCID CLNIEEIKIG RFKIIYVLNS IYNNTRVHIS TYVENNGIIE TTSGLFESSV 

       130        140        150        160        170        180 
WLEREIWDMF GIYFEKHPDL RRILTDYGFV GYPLKKDFPI TGYLEVYYDV ADKKIIYKPI 

       190        200 
ELMQEYRNYN FGAVWGDYER KVYLENIIK

Q2LCR4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools