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UniProtKB/Swiss-Prot entry Q2KWH7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_BORA1
Primary accession number Q2KWH7
Secondary accession numbers None
Integrated into Swiss-Prot on October 17, 2006
Sequence was last modified on March 7, 2006 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 21)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: BAV2671
From
Bordetella avium (strain 197N) [TaxID: 360910] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01927-05; PubMed=16885469 [NCBI, ExPASy, EBI, Israel, Japan]
Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M.;
"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction.";
J. Bacteriol. 188:6002-6015(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM167904; CAJ50282.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_787170.1; -.
3D structure databases
SMR Q2KWH7; 1-327.
ModBase Q2KWH7.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q2KWH7.
Genome annotation databases
GeneID 6267587; -.
GenomeReviews AM167904_GR; BAV2671.
KEGG bav:BAV2671; -.
NMPDR fig|521.1.peg.295; -.
Phylogenomic databases
HOGENOM Q2KWH7; -.
Genome annotation databases
CMR Q2KWH7; BAV2671.
Other
ProtoNet Q2KWH7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   338  338     Ketol-acid reductoisomerase. PRO_0000252751
ACT_SITE   107   107        Potential. 
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 36360 Da [This is the MW of the unprocessed precursor] CRC64: AD3E63C226F58EFC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKVFYDKDCD LSLVKGKTVA IIGYGSQGHA HALNLHESGV KVVVGLRKGG ASWNKAANAG 

        70         80         90        100        110        120 
LEVAEVAEAV KRADVVMMLL PDENIAAVYR DEVHANIKPG AALAFAHGFN VHYGQVVPRE 

       130        140        150        160        170        180 
DIDVIMVAPK APGHTVRSTY SQGGGVPHLV AVYQDKSGAA RDVALSYASA NGGGRAGIIE 

       190        200        210        220        230        240 
TNFREETETD LFGEQAVLCG GTVELIKAGF DTLVEAGYAP EMAYFECLHE LKLIVDLIYE 

       250        260        270        280        290        300 
GGIANMNYSI SNNAEFGEYE TGPKVVTDET RKAMRQCLTD IQTGEYAKRF ILENAAGAPT 

       310        320        330 
LTSRRRINAE SQIEVVGAKL RAMMPWIAAN KLVDKSKN 

Q2KWH7 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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