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UniProtKB/Swiss-Prot entry Q2KJC9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AL7A1_BOVIN
Primary accession number Q2KJC9
Secondary accession numbers None
Integrated into Swiss-Prot on June 27, 2006
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    September 2, 2008 (Entry version 24)
Name and origin of the protein
Protein name Alpha-aminoadipic semialdehyde dehydrogenase
Synonyms Alpha-AASA dehydrogenase
EC 1.2.1.31
Delta1-piperideine-6-carboxylate dehydrogenease
P6c dehydrogenase
Aldehyde dehydrogenase family 7 member A1
Antiquitin-1
Gene name
Name: ALDH7A1
From
Bos taurus (Bovine) [TaxID: 9913] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=Hereford;
TISSUE=Heart ventricle;
NIH - Mammalian Gene Collection (MGC) project;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC105406; AAI05407.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
UniGene Bt.22086
3D structure databases
SMR Q2KJC9; 1-498, 2-499.
ModBase Q2KJC9.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; FALSE_NEG.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q2KJC9.
Genome annotation databases
Ensembl ENSBTAG00000009646; Bos taurus. [Contig view]
Phylogenomic databases
HOVERGEN Q2KJC9; -.
Other
ProtoNet Q2KJC9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   511  510     Alpha-aminoadipic semialdehyde dehydrogenase. PRO_0000244567
NP_BIND   246   251  6     NAD (By similarity). 
ACT_SITE   268   268        Proton acceptor (By similarity). 
ACT_SITE   302   302        Nucleophile (By similarity). 
SITE   167   167  1     Transition state stabilizer (By similarity). 
Sequence information
Length: 511 AA [This is the length of the unprocessed precursor] Molecular weight: 55379 Da [This is the MW of the unprocessed precursor] CRC64: 26951EAAEE6F9505 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSTLLINQPQ YAWLKELGLR EENDGVYNGS WGGRGEVITT YCPANNEPIA RVRQASMADY 

        70         80         90        100        110        120 
EETVEKAREA WSIWADVPAP KRGEVVRQIG DALREKIQVL GSLVSLEMGK ILVEGVGEVQ 

       130        140        150        160        170        180 
EYVDVCDYAV GLSRMIGGPI LPSERPGHAL IEQWNPVGLV GIITAFNFPV AVYGWNNAIA 

       190        200        210        220        230        240 
MICGNACLWK GAPTTSLISV AVTKIIAKVL EDNKLPGAIC SLTCGGADIG TAMAKDERVD 

       250        260        270        280        290        300 
LLSFTGSTQV GKQVALMVQE RFGRSLLELG GNNAIIAFED ADLSLVVPSA LFAAVGTAGQ 

       310        320        330        340        350        360 
RCTTARRLFL HESIHDEVVN RLKKAYAQIR VGNPWDSNVL YGPLHTKQAV SMFLGAVEEA 

       370        380        390        400        410        420 
KKEGGTVVYG GKVMDRPGNY VEPTIVTGLD HDASIVHTET FAPILYVFKF KNEDEVFAWN 

       430        440        450        460        470        480 
NEVKQGLSSS IFTKDMGRIF RWLGPKGSDC GIVNVNIPTS GAEIGGAFGG EKHTGGGRES 

       490        500        510 
GSDAWKQYMR RSTCTINYSK DLPLAQGIKF Q 

Q2KJC9 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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