NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Lantern;
DOI=10.1016/S0167-4838(96)00211-7; PubMed=9165098 [NCBI, ExPASy, EBI, Israel, Japan]
Ye L., Buck L.M., Schaeffer H.J., Leach F.R.;
"Cloning and sequencing of a cDNA for firefly luciferase from Photuris pennsylvanica.";
Biochim. Biophys. Acta 1339:39-52(1997).

Comments

FUNCTION: Produces green light with a wavelength of 562 nm (By similarity).
CATALYTIC ACTIVITY: Photinus luciferin + O₂ + ATP = oxidized Photinus luciferin + CO₂ + AMP + diphosphate + light.
COFACTOR: Magnesium (By similarity).
SUBCELLULAR LOCATION: Peroxisome (By similarity).
SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

U31240; AAB60897.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P08659; 1LCI. [HSSP ENTRY / PDB]

ModBase

Q27757.

Family and domain databases

InterPro

IPR000873; AMP-dep_Synth/Lig.
Graphical view of domain structure.

Pfam

PF00501; AMP-binding; 1.
Pfam graphical view of domain structure.

PRINTS

PR00154; AMPBINDING.

PROSITE

PS00455; AMP_BINDING; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Luminescence; Magnesium; Metal-binding; Monooxygenase; Oxidoreductase; Peroxisome; Photoprotein.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 545`	`545`	`Luciferin 4-monooxygenase.`	`PRO_0000193146`
`MOTIF`	`543 545`	`3`	`Microbody targeting signal (Potential).`

Sequence information

Length: 545 AA [This is the length of the unprocessed precursor]

Molecular weight: 60649 Da [This is the MW of the unprocessed precursor]

CRC64: F0FE4E828047C26E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MEDKNILYGP EPFHPLADGT AGEQMFYALS RYADISGCIA LTNAHTKENV LYEEFLKLSC 

        70         80         90        100        110        120 
RLAESFKKYG LKQNDTIAVC SENGLQFFLP LIASLYLGII AAPVSDKYIE RELIHSLGIV 

       130        140        150        160        170        180 
KPRIIFCSKN TFQKVLNVKS KLKYVETIII LDLNEDLGGY QCLNNFISQN SDINLDVKKF 

       190        200        210        220        230        240 
KPNSFNRDDQ VALVMFSSGT TGVSKGVMLT HKNIVARFSH CKDPTFGNAI NPTTAILTVI 

       250        260        270        280        290        300 
PFHHGFGMTT TLGYFTCGFR VALMHTFEEK LFLQSLQDYK VESTLLVPTL MAFFPKSALV 

       310        320        330        340        350        360 
EKYDLSHLKE IASGGAPLSK EIGEMVKKRF KLNFVRQGYG LTETTSAVLI TPDTDVRPGS 

       370        380        390        400        410        420 
TGKIVPFHAV KVVDPTTGKI LGPNETGELY FKGDMIMKSY YNNEEATKAI INKDGWLRSG 

       430        440        450        460        470        480 
DIAYYDNDGH FYIVDRLKSL IKYKGYQVAP AEIEGILLQH PYIVDAGVTG IPDEAAGELP 

       490        500        510        520        530        540 
AAGVVVQTGK YLNEQIVQNF VSSQVSTAKW LRGGVKFLDE IPKGSTGKID RKVLRQMFEK 


HKSKL

Q27757 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools