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UniProtKB/Swiss-Prot entry Q20XN0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MDH2_RHOPB
Primary accession number Q20XN0
Secondary accession numbers None
Integrated into Swiss-Prot on June 27, 2006
Sequence was last modified on April 18, 2006 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 20)
Name and origin of the protein
Protein name Malate dehydrogenase 2
Synonym EC 1.1.1.37
Gene name
Name: mdh2
OrderedLocusNames: RPC_4584
From
Rhodopseudomonas palustris (strain BisB18) [TaxID: 316056] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Rhodopseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.;
"Complete sequence of Rhodopseudomonas palustris BisB18.";
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000301; ABD90106.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_534425.1; -.
3D structure databases
ModBase Q20XN0.
Enzyme and pathway databases
BioCyc RPAL316056:RPC_4584-MON; -.
Ontologies
GO
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0030060; Molecular function: L-malate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from InterPro).
GO:0006108; Biological process: malate metabolic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006099; Biological process: tricarboxylic acid cycle (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00487; -; 1.
PBIL [Tree]
InterPro IPR001557; L-lactate/malate_DHase.
IPR001236; Lactate/malate_DHase.
IPR015955; Lactate_DHase/Glyco_Ohase_4_C.
IPR011275; Malate_DHase_NAD-dep_bac.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.90.110.10; lact_mal_DH; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02866; Ldh_1_C; 1.
PF00056; Ldh_1_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000102; Lac_mal_DH; 1.
PRINTS PR00086; LLDHDRGNASE.
TIGRFAMs TIGR01763; MalateDH_bact; 1.
ProtoNet Q20XN0.
Genome annotation databases
GeneID 3971883; -.
GenomeReviews CP000301_GR; RPC_4584.
KEGG rpc:RPC_4584; -.
Phylogenomic databases
HOGENOM Q20XN0; -.
Genome annotation databases
CMR Q20XN0; RPC_4584.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   320  320     Malate dehydrogenase 2. PRO_0000241963
NP_BIND   10    15  6     NAD (By similarity). 
NP_BIND   119   121  3     NAD (By similarity). 
ACT_SITE   176   176        Proton acceptor (By similarity). 
BINDING   34    34        NAD (By similarity). 
BINDING   83    83        Substrate (By similarity). 
BINDING   89    89        Substrate (By similarity). 
BINDING   96    96        NAD (By similarity). 
BINDING   121   121        Substrate (By similarity). 
BINDING   152   152        Substrate (By similarity). 
Sequence information
Length: 320 AA [This is the length of the unprocessed precursor] Molecular weight: 33295 Da [This is the MW of the unprocessed precursor] CRC64: FB66148031961E30 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSRKKIVLAG AGQIGGTLAH LAMLHRLGDV TLLDVNANPP KGKALDLSHA AAVEGCDAVL 

        70         80         90        100        110        120 
TGTADQADIA GADVVIVTAG VPRRPGVDRD ALLAINLPVM ESIGTAIGRY CPDAFVICIT 

       130        140        150        160        170        180 
NPLDAMVWAL RRFSGLPPAR VVGMGGVLDS ARLRSFLAEA LGVSVTEVQA MTLGGHGDDM 

       190        200        210        220        230        240 
VPLVRQATVG GVPLPALVKM GWITQQAIDD IVQRTRTGGA EVVNLLWTSS AYYAPASAAI 

       250        260        270        280        290        300 
AMATSYLGDQ KRVFAASAAL SGQYGVDGLH VGVPVMIGAG GIEKIIELEF DDEEQRQFTR 

       310        320 
SVAAVAALVE DCKRLHRGLA
Q20XN0 in FASTA format

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